CAR-T（CAR-T）细胞疗法在非肿瘤性疾病中的应用
Chimeric antigen receptor T (CAR-T) cell therapy in non-oncological diseases.
CELL INTELLIGENCE · 肿瘤细胞治疗研究
肿瘤细胞治疗研究
粒细胞输注在优化难治性感染患者接受 CAR-T 细胞治疗候选资格中的作用
英文原题：The Role of Granulocyte Transfusions in Optimizing Candidacy for Chimeric Antigen Receptor T-cell Therapy in Patients With Treatment-refractory Infections.
查看英文原题
The Role of Granulocyte Transfusions in Optimizing Candidacy for Chimeric Antigen Receptor T-cell Therapy in Patients With Treatment-refractory Infections.
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中文摘要
尽管细胞疗法的进步改善了难治性白血病患者的预后，但严重感染可能阻碍其可及性。粒细胞输注联合抗微生物治疗，对于存在长期免疫抑制状态的白血病患者，可能是促进其成为CAR-T 细胞疗法候选者的安全选择。
展开英文摘要原文
While advancements in cellular therapy have improved outcomes for patients with refractory leukemia, severe infections may hinder access. Granulocyte transfusions, in combination with anti-microbial therapy, may be a safe option to facilitate candidacy for chimeric antigen receptor T-cell therapy in patients with leukemia and prolonged immune-compromised status.
论文信息
- 作者
- Tambaro FP、Ragoonanan D、Tewari P、Petropoulos D、Aung FM、Mahadeo KM、Khazal S
- 单位
- Department of Pediatrics, Pediatric Stem Cell Transplantation and Cellular Therapy, CARTOX Program.
- 期刊
- Journal of pediatric hematology/oncology2022 Mar 1
- 原文标识
- PubMed 33625094 · DOI 10.1097/MPH.0000000000002111