复发/难治性 CD5 阳性弥漫大 B 细胞淋巴瘤的 CAR T 细胞治疗较标准治疗产生更有利的结局
CAR T-cell therapy for relapsed/refractory CD5-positive diffuse large B-cell lymphoma yields more favorable outcomes than standard therapy.
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CAR T-cell therapy for relapsed/refractory CD5-positive diffuse large B-cell lymphoma yields more favorable outcomes than standard therapy.
Development of an in situ CAR-T cell protocol through optical and PSMA-targeted PET imaging.
原位T细胞转染方法克服了传统嵌合抗原受体(CAR)-T疗法相关的复杂性和高成本。
High-grade B-cell lymphoma, not otherwise specified: CNS involvement and outcomes in a multi-institutional series.
11例患者(7%)在诊断时存在基线CNS受累(软脑膜=6,实质=4,两者均有=1)。
Impact of CD5 expression on outcomes for chimeric antigen receptor-T cell therapy in relapsed and refractory diffuse large B-cell lymphoma.
这些数据表明,CD5 表达对 CAR-T 细胞治疗后的结局有负面影响。
Contemporary management of diffuse large B-cell lymphoma in Japan.
由专家或通过会诊网络对DLBCL进行准确的病理诊断至关重要,而一种新兴的基因组检测将有助于未来的精准诊疗方法。
CAR-T Cell Therapy for T-Cell Malignancies.
CAR-T 细胞疗法已经彻底改变了B细胞淋巴系统肿瘤的治疗,并在某些情况下改善了疾病结局。
Minimal/Measurable Disease Analysis in Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma by Flow Cytometry.
本文详细介绍了在纪念斯隆-凯特琳癌症中心开发的一种流式细胞术检测方法,该方法已证实在骨髓和外周血中能够持续达到高灵敏度(<0.01%的有核细胞),即使在CD19丢失或无法进行分析的情况下也是如此。
The effective and safe administration of Epcoritamab in relapsed CD19-CD5+ DLBCL following CAR-T therapy.
该病例凸显了 epcoritamab 联合减瘤治疗用于治疗 CAR-T 难治性 CD19 阴性 DLBCL 的潜力。
A case of successful CAR-T cell therapy for early isolated CNS recurrence of DLBCL with persistent CAR-T cells.
继发性中枢神经系统(CNS)淋巴瘤通常需要可穿透 CNS 的药物;然而,可用药物有限,疗效短暂且结局不佳。
Nanobody-derived bispecific CAR-T cell therapy enhances the anti-tumor efficacy of T cell lymphoma treatment.
T 细胞淋巴瘤(TCL)是一组高度异质性的疾病,预后差,5 年总生存率低。
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