肿瘤细胞治疗研究
DISEASE HUB
FOR TREATMENT
现在就能报名的(招募中)排在最前,共 0 项。同一状态内中国中心优先。信息来自 ClinicalTrials.gov、CDE 与 ChiCTR 公开登记。能否入组、费用与可及性,以登记原文和主治医生判断为准。
FOR RESEARCH
A phase 1 trial of CD123-directed chimeric antigen receptor T-cell therapy in adults with relapsed/refractory acute myeloid leukemia or blastic plasma
CD123 靶向 CAR-T 细胞疗法在 r/r AML 和 BPDCN 患者中是可行的,并显示出良好的安全性特征,包括既往接受过 alloHCT 的患者。尽管估计的总体完全缓解率不高,但这些发现为进一步优化 CD123 CAR-T 细胞设计、患者选择和联合策略提供了基础。
Quantifying target antigen-dependent CAR T-cell performance against AML.
The search for safe and effective CAR-T targets in AML.
Antibody format matters: A comparative analysis of VHH and scFv domains reveals superior in vivo CAR T cell function with VHH domains.
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