HER2 阳性乳腺癌辅助曲妥珠单抗治疗预后的影响因素
Influencing Factors of Prognosis in Adjuvant Trastuzumab Therapy for HER2-Positive Breast Cancer.
肿瘤细胞治疗研究
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Influencing Factors of Prognosis in Adjuvant Trastuzumab Therapy for HER2-Positive Breast Cancer.
Adjuvant treatments for stage I breast cancers of one centimeter or less.
Recurrence score prediction formula based on immunohistochemistry and biopsy data to predict response to neoadjuvant chemotherapy in estrogen receptor
Differential FGFR1 copy number status displays unique tumour immune microenvironment in triple-negative breast cancer.
Manual, digital, and AI tumour-infiltrating lymphocyte scoring: a secondary analysis of the APHINITY randomised trial.
标准化人工 sTIL 评分具有可重复性,数字和基于 AI 的方法尽管平台间仅呈中度相关,但显示出一致的预后分层及治疗获益分层的潜力。AI 空间指标提供了超越 sTIL 密度的补充信息,可支持更具可扩展性的免疫评估。未来需要在独立队列中验证这些方法,并阐明其在当代 HER2 靶向治疗分层中的临床效用。
Tumour-infiltrating lymphocytes differ across MammaPrint® classifications in breast cancer.
Advances in Targeting Immune Checkpoint Inhibitors and New Vaccination Strategies for Triple-negative Breast Cancers: An Update.
TNBC-TME 是免疫治疗的靶点。当前的免疫治疗策略利用针对 PD-1、PD-L1 和 CTLA-4 的免疫检查点抑制剂(ICIs)靶向 TNBC TME。此外,多项研究致力于开发针对 TNBC TME 中免疫抑制细胞和分子的疫苗。本综述重点介绍了减轻 TNBC 的免疫治疗策略的进展,特别关注靶向免疫抑制分子。
Microfluidic Cytotongue system enables early, label-free detection of CAR-T-induced mechanical softening in tumor spheroids.
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