CELL INTELLIGENCE · 肿瘤细胞治疗研究

CD19 CAR-T 细胞治疗滤泡性淋巴瘤后重度银屑病长期缓解

Long-term Remission of Severe Psoriasis Following CD19 CAR-T Cell Therapy for Follicular Lymphoma.

新一代 CD179a-CAR-T 细胞在临床前 B 细胞恶性肿瘤中展现强效且持久的抗肿瘤活性

Next-generation CD179a-CAR-T cells demonstrate potent and sustained anti-tumor activity in preclinical B-cell malignancies.

这些发现凸显了靶向 CD179a 的 CAR-T 细胞具有前景广阔的抗白血病潜力，兼具高特异性和良好的安全性特征。这项体外和体内研究支持将 CD179a-CAR-T 细胞疗法推进为 B 细胞白血病的下一代免疫治疗策略，值得进一步的临床前和临床开发。

急性淋巴细胞白血病（ALL）对 FDA 批准靶向治疗和免疫治疗反应的预测

Prediction of Response to FDA-Approved Targeted Therapy and Immunotherapy in Acute Lymphoblastic Leukemia (ALL).

靶向人 CD22 的治疗活性纳米抗体 CAR 的发现与临床前开发

Discovery and preclinical development of a therapeutically active nanobody-based chimeric antigen receptor targeting human CD22.

CD20 特异性 CAR-T 细胞的临床前比较分析：涵盖基于 1F5、Leu16 和 2F2 的抗原识别部分

Comparative Pre-Clinical Analysis of CD20-Specific CAR T Cells Encompassing 1F5-, Leu16-, and 2F2-Based Antigen-Recognition Moieties.

潜伏 EBV 再激活驱动 EBV 阴性直肠癌肿瘤组织来源 TIL（肿瘤浸润淋巴细胞）体外扩增过程中的异常 B 细胞增殖

Latent EBV reactivation drives aberrant B-cell proliferation during ex vivo tumor-infiltrating lymphocyte expansion from EBV-negative rectal cancer tu

B 细胞急性淋巴细胞白血病治疗性单克隆抗体研发的最新进展

Recent advances in monoclonal antibody development for treatment of B-cell acute lymphoblastic leukemia.

识别 CAR-T 细胞疗效与安全性的调节因素：系统综述与个体患者数据荟萃分析

Identifying Modifiers of CAR T-Cell Therapeutic Efficacy and Safety: A Systematic Review and Individual Patient Data Meta-Analysis.

结直肠癌和浸润性乳腺癌中 CAR-T 细胞治疗的临床新视角与挑战

Updated Clinical Perspectives and Challenges of Chimeric Antigen Receptor-T Cell Therapy in Colorectal Cancer and Invasive Breast Cancer.

探索针对人 B 细胞淋巴瘤的 CD19 靶向免疫治疗策略

Exploring CD19-targeted Immunotherapy Strategies for Human B-cell Lymphoma.