CELL INTELLIGENCE · 肿瘤细胞治疗研究

没有 BCMA？没问题：靶向 CD70 的 CAR-NK 细胞在高危骨髓瘤中展现前景

No BCMA? No Problem: A CD70-Targeting CAR-NK Cell Shows Promise in High-risk Myeloma.

靶向 CD70 的 CAR-NK 细胞克服 BCMA 下调并改善高危多发性骨髓瘤模型中的生存

CD70-Targeting CAR NK Cells Overcome BCMA Downregulation and Improve Survival in High-risk Multiple Myeloma Models.

抗 BCMA-CAR-IL15 NK 细胞阻止多发性骨髓瘤在骨髓中生长但随后出现髓外疾病

Anti-BCMA-CAR-IL15 natural killer cells prevent multiple myeloma growth in the bone marrow but allow subsequent emergence of extramedullary disease.

肿瘤预激 CD8⁺ 自然杀伤 T 样细胞作为复发/难治性多发性骨髓瘤的高效新型细胞疗法

Tumor-priming CD8(+) natural killer T-like cells as an efficient novel cell therapy for relapsed/refractory multiple myeloma.

TPNC 是一种通过肿瘤驱动的致敏产生的新型细胞毒性淋巴细胞产品。

抗 BCMA CAR-NK 细胞显示出对骨髓瘤细胞增强的溶细胞和分泌反应

Anti-BCMA CAR-NK Cells Reveal Enhanced Cytolytic and Secretory Responses Against Myeloma Cells.

用于多发性骨髓瘤的单 VHH 导向 BCMA CAR-NK 细胞

Single VHH-directed BCMA CAR-NK cells for multiple myeloma.

靶向 GPRC5D 的免疫治疗在复发/难治性多发性骨髓瘤中的最新进展：2022 ASH 年会更新

Immunotherapies targeting GPRC5D in relapsed or refractory multiple myeloma: latest updates from 2022 ASH Annual Meeting.

多发性骨髓瘤 CAR-NK 细胞治疗的最新进展：细胞来源与靶抗原的综合综述

State of the Art of CAR-NK Cell Therapy in Multiple Myeloma: A Comprehensive Review of Cell Sources and Target Antigens.

利用 CAR-NK 细胞对抗多发性骨髓瘤：当前格局与未来方向

Harnessing CAR-NK cells against multiple myeloma: current landscape and future directions.

CAR-NK 疗法正从一种有前景的概念演变为针对 MM 的现实治疗平台。

CAR-T 与 CAR NK 细胞的在靶脱瘤效应差异提示细胞治疗的疗效与安全性不同

Divergent on-target off-tumor effects by CAR T and CAR NK cells suggest different efficacy and safety of cell therapies.