Claudin 18.2 靶向:泛癌视角
Claudin 18.2 Targeting: A Pan-Cancer Perspective.
肿瘤细胞治疗研究
FRONTIER PAPERS
近 5 年肿瘤细胞治疗领域的研究论文。默认按评分排序(权威性 + 新鲜度)。
Claudin 18.2 Targeting: A Pan-Cancer Perspective.
Treatment sequence of stem cell delivered heterologous oncolytic virus impact on tumor microenvironment in immunocompetent ovarian cancer model.
异源 OV 的治疗顺序对肿瘤微环境有显著影响。NNV24+SNV1 促进强效抗肿瘤免疫并改善生存,而相反顺序则损害免疫激活和治疗反应。这些发现为基于 OV 的免疫疗法的合理排序建立了机制框架。
Tumor-specific immunological and pathological changes in layer chickens affected with ovarian adenocarcinoma.
Systems-Level Mapping of the Tumor Microenvironment Reveals Immune-Mediated Mechanisms and Potential Targets in Platinum-Resistant Ovarian Cancer.
这些发现强调了肿瘤微环境组分,特别是巨噬细胞和成纤维细胞,作为卵巢癌耐药的关键贡献因素的重要性,并建立了一个潜在的耐药特征用于生物标志物的发现。
Folate receptor-α targeted therapies in ovarian cancer: recent advances and emerging therapeutic strategies.
Olvi-Vec oncolytic immunotherapy and reversal of platinum resistance in ovarian cancer.
Olvi-Vec 治疗可有利地改变 OC 的 TME,并可能解释铂类再挑战后铂类耐药性的明显逆转。试验注册:ClinicalTrials.gov 标识符:NCT02759588。
SIRPα ablated iPSC-derived macrophages resist hypophagia and enhance mAb-dependent and CAR-mediated cytotoxicity of solid tumors.
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