CAR mRNA 工程化 T 细胞与巨噬细胞在清除 CD19⁺ 白血病细胞中的不同效应功能与协同作用
Distinct effector functions and synergy of CAR mRNA-engineered T cells and macrophages in the clearance of CD19(+) leukemia cells.
我们的研究结果凸显了 CAR-T 细胞优越的肿瘤细胞杀伤能力。
FRONTIER PAPERS
Distinct effector functions and synergy of CAR mRNA-engineered T cells and macrophages in the clearance of CD19(+) leukemia cells.
我们的研究结果凸显了 CAR-T 细胞优越的肿瘤细胞杀伤能力。
Engineering Immunity: Current Progress and Future Directions of CAR-T Cell Therapy.
CAR-NK Cells Generated with mRNA-LNPs Kill Tumor Target Cells In Vitro and In Vivo.
Two for one: targeting BCMA and CD19 in B-cell malignancies with off-the-shelf dual-CAR NK-92 cells.
在此,我们利用经临床验证的 NK-92 细胞系作为治疗性细胞来源,建立了一个易于获取且灵活的平台,用于生成高度功能化的双靶向 CAR-NK 细胞。
Immune responses and clinical outcomes following the third dose of SARS-CoV-2 mRNA-BNT162b2 vaccine in advanced breast cancer patients receiving targe
我们的结果证实,CDK4/6 抑制剂削弱了对 tozinameran 的免疫应答,尽管接种了第三剂疫苗,仍增加了突破性感染的风险。当前证据建议继续努力为最脆弱的癌症患者提供加强免疫接种,包括正在接受 CDK4/6 抑制治疗的晚期乳腺癌患者。
Immune Responses to SARS-CoV-2 Vaccination in Young Patients with Anti-CD19 Chimeric Antigen Receptor T Cell-Induced B Cell Aplasia.
Engineering mRNA CAR-T Cells for Cancer Immunotherapy.
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