CELL INTELLIGENCE · 肿瘤细胞治疗研究

药理学的 HIF 稳定化激活共刺激受体表达，以提高过继性 T 细胞疗法的抗肿瘤疗效

Pharmacologic HIF stabilization activates costimulatory receptor expression to increase antitumor efficacy of adoptive T cell therapy.

T 细胞受体组分的胞质染色可实现表面 CD3 阴性 T 细胞肿瘤谱系与克隆性的高效评估

Cytoplasmic staining of T cell receptor components enables efficient assessment of lineage and clonality in surface CD3-negative T cell neoplasms.

慢性髓性白血病急变期表现为早期前体 T 细胞急性淋巴细胞白血病

Blast phase of chronic myeloid leukemia presenting as early T-cell precursor acute lymphoblastic leukemia.

CML-BP 患者可能伴有 ETP-ALL。这些患者通常临床病程侵袭性强，需要强化治疗，并可能从干细胞移植中获益。