CELL INTELLIGENCE · 肿瘤细胞治疗研究

靶向 B7-H3-CAR-T 细胞中的 Regnase-1 重编程肿瘤微环境并增强骨肉瘤抗肿瘤疗效

Targeting Regnase-1 in B7-H3-CAR T cells reprograms the tumor microenvironment and enhances antitumor efficacy for osteosarcoma.

骨肉瘤的基因免疫治疗：从溶瘤载体到工程化免疫细胞

Gene-based immunotherapy in osteosarcoma: from oncolytic vectors to engineered immune cells.

重编程过继细胞治疗骨肉瘤：工程化、疫苗接种与肿瘤微环境重塑

Reprogramming adoptive cell therapy for osteosarcoma: engineering, vaccination, and tumor microenvironment remodeling.

骨肉瘤“冷转热”的概念蓝图：从肿瘤微环境分层假说到适应性治疗前景

A conceptual blueprint for "turning cold to hot" in Osteosarcoma: from TME stratification hypotheses to adaptive therapeutic prospects.

靶向 CD70 的 CAR-T/NK 治疗：原理、进展和未来方向

CD70-targeted CAR-T/NK therapy: Rationale, advances, and future directions.

RAE1 装甲 DC 疫苗增强 NKG2D-CAR-T 细胞诱导的抗实体瘤治疗

RAE1-armoured DC vaccine boosts NKG2D-CAR-T cells elicited anti-solid tumour treatment.

靶向 Regnase-1 释放 CAR-T 细胞抗骨肉瘤活性并形成促炎肿瘤微环境

Targeting Regnase-1 unleashes CAR T cell antitumor activity for osteosarcoma and creates a proinflammatory tumor microenvironment.

肉瘤的基因与细胞治疗：综述

Gene and Cell Therapy for Sarcomas: A Review.

挖掘新兴骨肉瘤治疗中免疫学方法的复杂性：一项结合最新临床试验的综合叙述性综述

Digging Through the Complexities of Immunological Approaches in Emerging Osteosarcoma Therapeutics: A Comprehensive Narrative Review with Updated Clin

用表达靶向 EphA2 CAR 的 mRNA 工程化 NK 细胞增强抗肉瘤免疫

Enhancement of anti-sarcoma immunity by NK cells engineered with mRNA for expression of a EphA2-targeted CAR.

该研究为 EphA2 靶向 CAR-NK 细胞治疗在一系列儿童肉瘤中的临床评价提供了基础依据。