CELL INTELLIGENCE · 肿瘤细胞治疗研究

EGFR806-CAR-T 细胞局部区域输注治疗复发/难治性儿童中枢神经系统肿瘤：已完成的 BrainChild02 I 期临床试验结果

Locoregional infusion of EGFR806-CAR T cells for recurrent or refractory pediatric CNS tumors: Results of the completed BrainChild02 phase 1 clinical

颅内输注 EGFR806-CAR-T 细胞在测试剂量下可耐受，最佳反应为疾病稳定。EGFR 是针对儿童脑肿瘤，特别是高级别胶质瘤的细胞治疗的潜在有用靶点。

儿童脑肿瘤的局部区域和全身过继性细胞疗法：CAR-T、TCR 工程 T 细胞和 NK 细胞策略的系统综述

Locoregional and systemic adoptive cellular therapies for pediatric brain tumors: a systematic review of CAR‑T, TCR‑engineered T cells, and NK cell st

原发性脑肿瘤的 CAR-T 细胞治疗：当前研究与未来

CAR T Cell Therapy in Primary Brain Tumors: Current Investigations and the Future.

弥漫性中线胶质瘤（DMG）中分子靶向治疗诱导的免疫肽组鉴定

Identification of molecularly targeted therapy-induced immunopeptidome in diffuse midline glioma (DMG).

MTX-241F 改变了胶质瘤免疫肽组，揭示 H2B1K、脑富集免疫肽以及治疗诱导的免疫肽是免疫可见的靶点。

儿童大脑半球高级别胶质瘤与 H3.3-G34 突变：生物学特征与新治疗策略的文献综述

Pediatric Hemispheric High-Grade Gliomas and H3.3-G34 Mutation: A Review of the Literature on Biological Features and New Therapeutic Strategies.

综述：胶质瘤微环境昼夜节律调节的治疗方法

Review: therapeutic approaches for circadian modulation of the glioma microenvironment.

儿童肉瘤中的 CAR-T 细胞治疗与免疫抑制性肿瘤微环境

Chimeric Antigen Receptor T cell Therapy and the Immunosuppressive Tumor Microenvironment in Pediatric Sarcoma.

局部区域 CAR-T 细胞治疗儿童中枢神经系统肿瘤：研究性药物服务药房工作

Locoregional CAR T Cells for the Treatment of CNS Tumors in Children: Investigational Drug Service Pharmacy Activities.

随着过继性免疫治疗领域的不断发展，并持续为致命性 CNS 恶性肿瘤患者带来希望，关注改进 CAR-T 细胞递送的准备步骤至关重要。