通过高分辨率质谱和新算法预测快速直接发现功能性肿瘤特异性新抗原
Rapid and direct discovery of functional tumor specific neoantigens by high resolution mass spectrometry and novel algorithm prediction.
尽管免疫细胞疗法已经改变了癌症治疗格局,但与NHL和MM等血液系统恶性肿瘤相比,在实体瘤中取得同等成功仍然是一项重大挑战。
FRONTIER PAPERS
Rapid and direct discovery of functional tumor specific neoantigens by high resolution mass spectrometry and novel algorithm prediction.
尽管免疫细胞疗法已经改变了癌症治疗格局,但与NHL和MM等血液系统恶性肿瘤相比,在实体瘤中取得同等成功仍然是一项重大挑战。
Latent EBV reactivation drives aberrant B-cell proliferation during ex vivo tumor-infiltrating lymphocyte expansion from EBV-negative rectal cancer tu
近期研究强调了CAR-T和TIL(肿瘤浸润淋巴细胞)治疗中疱疹病毒相关风险,尤其是HHV6和Epstein Barr病毒(EBV),部分原因是体外细胞操作。
A Review of CAR T Cells and Adoptive T-Cell Therapies in Lymphoid and Solid Organ Malignancies.
嵌合抗原受体(CAR)T细胞是经过基因工程改造的T淋巴细胞,其表达一种识别肿瘤细胞表面抗原的合成受体,从而使该T淋巴细胞杀伤肿瘤细胞。
Applied Cardio-Oncology in Hematological Malignancies: A Narrative Review.
血液系统恶性肿瘤领域的应用心脏肿瘤学,是指为血液肿瘤患者,尤其是白血病、淋巴瘤和多发性骨髓瘤患者,整合心血管照护与管理。
Cardiac Toxicity Associated with Cancer Immunotherapy and Biological Drugs.
肿瘤免疫治疗对改善肿瘤患者的预后有显著贡献。
Genetically engineered T cell and tumour-infiltrating lymphocyte therapies.
近年来,血液肿瘤学取得了重大进展,尤其是通过开发 CAR-T 细胞和TIL(肿瘤浸润淋巴细胞)疗法等创新免疫治疗手段。
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