CELL INTELLIGENCE · 肿瘤细胞治疗研究

靶向急性髓系白血病中的表观遗传-免疫轴：当前进展与未来方向

Targeting the Epigenetic-Immune Axis in Acute Myeloid Leukemia: Current Advances and Future Directions.

癌症免疫治疗学会（SITC）关于急性白血病免疫治疗的临床实践指南，2.0 版

Society for Immunotherapy of Cancer (SITC) clinical practice guideline on immunotherapy for the treatment of acute leukemia, version 2.0.

CD84 在急性髓系白血病不同疾病阶段和白血病亚群中的表达

CD84 Expression Across Disease Stages and Leukemic Subpopulations in Acute Myeloid Leukemia.

结合现有的临床前和临床证据，这些发现支持继续评估靶向CD84的免疫疗法，包括CAR T细胞疗法，在AML中的应用。

免疫检查点敲除筛选揭示 TIGIT-CD155 相互作用是急性髓系白血病中适配体 CAR-T 细胞功能的重要调节因子

Immune checkpoint knockout screen reveals TIGIT-CD155 interaction as a significant modulator of adapter CAR-T cell function in acute myeloid leukemia.

Agrimol B 通过靶向 EGFR/ERK1/2 信号通路并激活 SIRT1，在急性单核细胞白血病中诱导凋亡和铁死亡

Agrimol B induces apoptosis and ferroptosis in acute monocytic leukemia by targeting EGFR/ERK1/2 signaling and activating SIRT1.

接受 CAR-T 细胞治疗或其他系统性抗肿瘤治疗的多发性骨髓瘤患者的第二原发恶性肿瘤风险：一项真实世界对比研究

Second Primary Malignancy Risk in Patients with Multiple Myeloma Receiving CAR T-cell Therapy or Other Systemic Anticancer Treatments: A Real-World Co

在这一随访时间相对较短的真实世界数据集中，与其他全身性抗肿瘤治疗相比，多发性骨髓瘤患者在接受 CAR-T 治疗后似乎具有更高的血液系统第二原发恶性肿瘤风险。

靶向 BLVRB 克服单核细胞性急性髓系白血病中的免疫抑制并增强免疫治疗

Targeting BLVRB Overcomes Immunosuppression and Potentiates Immunotherapy in Monocytic Acute Myeloid Leukemia.

从高比例急性髓系白血病原始细胞的白细胞单采物中学术制备抗 CD19 CAR-T 细胞

Academic manufacturing of anti-CD19 CAR-T cells from a leukapheresis with a high proportion of acute myeloid leukaemia blasts.

以双特异性抗体 XmAb 18968 靶向 CD38 治疗复发/难治性急性髓系白血病和 T 细胞急性淋巴细胞白血病患者

Targeting CD38 with bispecific antibody XmAb 18968 in patients with relapsed/refractory acute myeloid leukemia and T-cell acute lymphoblastic leukemia

CD84 表达可区分维奈克拉治疗反应并揭示耐药急性髓系白血病中的可靶向脆弱点

CD84 expression stratifies venetoclax response and reveals a targetable vulnerability in resistant acute myeloid leukemia.