携带 BLM 突变的 DLBCL 患者在接受 CD19/CD22 双特异性 CAR-T 细胞治疗后发生继发性外周 T 细胞淋巴瘤
Secondary peripheral T-cell lymphoma in a patient with DLBCL harboring BLM mutation following CD19/CD22 bispecific CAR-T cell therapy.
FRONTIER PAPERS
Secondary peripheral T-cell lymphoma in a patient with DLBCL harboring BLM mutation following CD19/CD22 bispecific CAR-T cell therapy.
Adult acute lymphoblastic leukemia: incorporation of recent advances into current treatment strategies.
A CD22-specific T-cell receptor enables effective adoptive T-cell therapy for B-cell malignancies.
AI-guided CAR designs and targeted pathway modulation to enhance multi-antigen CAR T cell durability and overcome antigen escape.
CAR T cells: the missing piece needed to improve outcomes for children with cancer?
Immunotherapy in B-Cell Acute Lymphoblastic Leukemia.
Advancements in diagnosis and treatments of acute leukemia.
CD22 as a Target for Hematological Malignancies and Autoimmune Diseases.
Association of baseline immune cell composition with CAR-T cell expansion and survival in Relapsed/Refractory large B-Cell lymphoma.
基线免疫细胞组成可能与 R/R 大 B 细胞淋巴瘤中 CAR-T 的扩增和结局相关。
Management of Adult Acute Lymphoblastic Leukemia: A Review.
ALL 的治疗正在迅速变化。研究者已经评估了一线及后线方案,采用酪氨酸激酶抑制剂与免疫治疗的联合方案,化疗强度更低或不再使用化疗。未来研究将评估 CD19、CD20 和 CD22 多靶点抗体及 CAR-T 细胞疗法、新型抗体制剂,以及强度更低/疗程更短的方案。
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