CELL INTELLIGENCE · 肿瘤细胞治疗研究

iPSC 来源的 MUC1 靶向 CAR-NK 细胞对食管鳞状细胞癌的临床前疗效

Preclinical efficacy of iPSC-derived MUC1-targeted CAR-NK cells against esophageal squamous cell carcinoma.

iPSC来源的MUC1靶向CAR-NK细胞对人ESCC发挥强效且特异性的抗肿瘤作用，支持这种现货型细胞疗法的临床转化。

诱导多能干细胞衍生并经工程化改造的 CD276 靶向 CAR-NK 细胞抗人食管鳞状细胞癌的疗效

Efficacy of the induced pluripotent stem cell derived and engineered CD276-targeted CAR-NK cells against human esophageal squamous cell carcinoma.

iPSC CD276靶向CAR-NK细胞在多种临床前模型中成功治疗表达CD276的ESCC所展现的疗效，表明它们对治疗表达CD276的ESCC患者具有巨大的治疗潜力。

CD22 是食管鳞状细胞癌 CAR-NK 细胞治疗的潜在靶点

CD22 is a potential target of CAR-NK cell therapy for esophageal squamous cell carcinoma.

CD22 是 ESCC 中可被 CAR-NK 细胞靶向的潜在肿瘤表面抗原。