工程化 CAR-T 来源外泌体共递送 miR-145 与细胞毒性蛋白用于靶向实体瘤治疗
Engineered CAR-T-Derived Exosomes Co-Delivering miR-145 and Cytotoxic Proteins for Targeted Solid Tumour Therapy.
CAR-T 细胞疗法在血液系统恶性肿瘤中展现出显著疗效,但在实体瘤中仍受限于肿瘤渗透不足、免疫抑制微环境及细胞因子释放综合征(CRS)风险。
FRONTIER PAPERS
Engineered CAR-T-Derived Exosomes Co-Delivering miR-145 and Cytotoxic Proteins for Targeted Solid Tumour Therapy.
CAR-T 细胞疗法在血液系统恶性肿瘤中展现出显著疗效,但在实体瘤中仍受限于肿瘤渗透不足、免疫抑制微环境及细胞因子释放综合征(CRS)风险。
A novel microenvironment regulated system CAR-T (MRS.CAR-T) for immunotherapeutic treatment of esophageal squamous carcinoma.
CAR-T 细胞免疫治疗在血液系统恶性肿瘤的治疗中已取得令人鼓舞的疗效。
Efficacy of the induced pluripotent stem cell derived and engineered CD276-targeted CAR-NK cells against human esophageal squamous cell carcinoma.
iPSC CD276靶向CAR-NK细胞在多种临床前模型中成功治疗表达CD276的ESCC所展现的疗效,表明它们对治疗表达CD276的ESCC患者具有巨大的治疗潜力。
CD22 is a potential target of CAR-NK cell therapy for esophageal squamous cell carcinoma.
CD22 是 ESCC 中可被 CAR-NK 细胞靶向的潜在肿瘤表面抗原。
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