衰老相关细胞与基因的整合分析鉴定 UGT1A7 为肺鳞状细胞癌的预后和治疗靶点
Integrative profiling of senescence-associated cells and genes identifies UGT1A7 as a prognostic and therapeutic target in Lung squamous cell carcinom
肺鳞状细胞癌(LUSC)是非小细胞肺癌的一种常见亚型,主要发生于老年人群,并与衰老相关的生物学过程密切相关。
FRONTIER PAPERS
Integrative profiling of senescence-associated cells and genes identifies UGT1A7 as a prognostic and therapeutic target in Lung squamous cell carcinom
肺鳞状细胞癌(LUSC)是非小细胞肺癌的一种常见亚型,主要发生于老年人群,并与衰老相关的生物学过程密切相关。
Risk Factors for COVID-19-Related Hospitalization and Death in Patients With Cancer: The National Cancer Institute COVID-19 in Cancer Patients Study (
这项前瞻性队列研究的结果显示,COVID-19对癌症患者产生了显著影响,包括住院、治疗中断和死亡。
Mechanisms and strategies of immunosenescence effects on non-small cell lung cancer (NSCLC) treatment: A comprehensive analysis and future directions.
非小细胞肺癌(NSCLC)是肺癌中最常见的类型,仍然是全球癌症相关死亡的主要原因之一,尤其是在老年人群中。
NK cell transfer overcomes resistance to PD-(L)1 therapy in aged mice.
我们的研究发现,老年患者对免疫治疗的敏感性降低,老年小鼠中亦是如此。
Anti-CD30 CAR T cells as consolidation after autologous haematopoietic stem-cell transplantation in patients with high-risk CD30(+) lymphoma: a phase
抗CD30 CAR-T细胞输注作为BEAM和自体HSCT后的巩固治疗是安全的,毒性发生率低,在高复发风险的霍奇金淋巴瘤患者中显示出令人鼓舞的初步活性,凸显了开展更大规模研究以证实这些发现的必要性。
Phase 1/2 study of monalizumab plus durvalumab in patients with advanced solid tumors.
尽管疗效有限,monalizumab联合durvalumab耐受性良好,且在外周血和TME中观察到了令人鼓舞的免疫激活。
Immunotherapy (excluding checkpoint inhibitors) for stage I to III non-small cell lung cancer treated with surgery or radiotherapy with curative inten
评估在I至III期接受根治性放疗或手术的局部NSCLC患者中免疫治疗(不包括检查点抑制剂)的有效性和安全性。
An update on the clinical trial research of immunotherapy for glioblastoma.
采用当前标准治疗,中位总生存期不足 2 年。
CAR-NK Cell Biology and Engineering for Solid Tumors, With a Focus on Lung Cancer.
过去十年间,嵌合抗原受体(CAR)T细胞疗法彻底改变了肿瘤免疫治疗格局,在儿童和成人复发或难治性血液系统恶性肿瘤的治疗中均展现出显著疗效。
Current Status and Challenges of Vaccination Therapy for Glioblastoma.
胶质母细胞瘤(GBM),也称为IV级星形细胞瘤,是成人中最常见且致命的中枢神经系统恶性肿瘤。
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