CELL INTELLIGENCE · 肿瘤细胞治疗研究

一种工程化腺相关病毒变体实现人 T 细胞的高效基因编辑

An Engineered Adeno-Associated Virus Variant Enables Efficient Gene Editing in Human T Cells.

CAR-T 细胞治疗在儿童、青少年和年轻成人癌症患者中的关键作用

The quintessential role for CAR T cell therapy in children, adolescents and young adults with cancer.

2025 年儿童肿瘤学东部与地中海双年会议亮点：推动东地中海地区儿童肿瘤学发展

Highlights From the 2025 Pediatric Oncology East and Mediterranean Biennial Conference: Advancing Pediatric Oncology Across the Eastern Mediterranean.

2025 年 POEM 双年会议重申了该网络作为推动东地中海地区儿童癌症诊疗进步催化剂的角色。

CAR mRNA 工程化 T 细胞与巨噬细胞在清除 CD19⁺ 白血病细胞中的不同效应功能与协同作用

Distinct effector functions and synergy of CAR mRNA-engineered T cells and macrophages in the clearance of CD19(+) leukemia cells.

我们的研究结果凸显了 CAR-T 细胞优越的肿瘤细胞杀伤能力。

CRISPR 在医学中的应用：临床试验与治疗应用的系统综述

CRISPR in Medicine: A Systematic Review of Clinical Trials and Therapeutic Applications.

T 细胞基因转移与基因组编辑用于癌症免疫治疗：从异基因 HSCT 到 TCR 基因编辑

Gene transfer and genome editing of T cells for cancer immunotherapy: from allogeneic HSCT to TCR gene editing.

急性髓系白血病治疗的靶向与表观遗传治疗

Targeted and epigenetic therapies for acute myeloid leukemia treatment.

急性髓系白血病药物递送与治疗策略的最新进展

Recent advances in drug delivery and treatment strategies for acute myeloid leukemia.

一项针对异基因造血细胞移植后患有活动性疾病的急性髓系白血病患者的 WT1 特异性 TCR 基因治疗的 I/II 期试验：向 NK 样表型偏移损害 T 细胞功能和持续性

A phase I/II trial of WT1-specific TCR gene therapy for patients with acute myeloid leukemia and active disease post-allogeneic hematopoietic cell tra

溶瘤病毒与 CAR-T 细胞基因治疗的进展及治疗相关分组

Advances in Gene Therapy with Oncolytic Viruses and CAR-T Cells and Therapy-Related Groups.