肿瘤细胞治疗研究
英文原题：Highlights From the 2025 Pediatric Oncology East and Mediterranean Biennial Conference: Advancing Pediatric Oncology Across the Eastern Mediterranean.
2025 年 POEM 双年会议重申了该网络作为推动东地中海地区儿童癌症诊疗进步催化剂的角色。
目的：POEM（东部和地中海儿科肿瘤学）双年会议通过科学交流、协作研究、能力建设和政策参与，作为推动区域儿童癌症照护发展的平台。2025年第四届科学会议旨在展示区域创新、加强合作伙伴关系，并使各项策略与世界卫生组织（WHO）全球儿童癌症倡议（GICC）保持一致。 方法：本报告总结了第4届POEM双年会议的科学、临床和教育内容。会议于2025年4月30日至5月3日在约旦安曼举行，主题为“发挥区域优势，改善公平性、可及性和照护质量”。会议议程包括全体讲座、专题研讨会、口头摘要、海报、专家交流和专题工作坊。 结果：会议吸引来自24个国家的351名代表，包括医生、护士、研究人员、政策制定者和倡导者。科学亮点包括首次报告中低收入环境下CAR-T细胞疗法区域多中心结局、急性淋巴细胞白血病最新生存数据，以及单倍体和去T细胞移植物造血细胞移植进展。专题会议讨论了中枢神经系统肿瘤、淋巴瘤、生存者照护、基因疗法和定性研究。倡导论坛强调流离失所和受冲突影响人群的公平性与治疗可及性。区域倡议包括加强POEM姑息治疗工作，并就符合WHO GICC的癌症早期检测策略达成共识。会前和会后人工智能、肉瘤管理、护理领导力及视网膜母细胞瘤工作坊提供了实操培训，强化区域能力建设。工作坊评估显示学习成果良好，且学员很可能改变实践。 结论：2025年POEM双年会议再次确认了该网络作为推动东部地中海地区儿童癌症照护催化平台的作用。通过将科学进展与公平性、可及性和政策改革策略结合，POEM持续加速实现全球目标：到2030年使所有儿童癌症患者的生存率至少达到60%。
PURPOSE: The Pediatric Oncology East and Mediterranean (POEM) Biennial Conference serves as a regional platform to advance childhood cancer care through scientific exchange, collaborative research, capacity building, and policy engagement. The 2025 Fourth Scientific Meeting aimed to showcase regional innovations, strengthen partnerships, and align strategies with the WHO Global Initiative for Childhood Cancer (GICC). METHODS: This report summarizes the scientific, clinical, and educational content of the 4th POEM Biennial Conference, held April 30-May 3, 2025, in Amman, Jordan, under the theme Harnessing Regional Strengths to Improve Equity, Access, and Quality Care . The program included plenary lectures, symposia, oral abstracts, posters, expert sessions, and focused workshops. RESULTS: The meeting attracted 351 delegates from 24 countries, including physicians, nurses, researchers, policymakers, and advocates. Scientific highlights featured the first regional multicenter outcomes of chimeric antigen receptor T-cell (CAR-T) therapy in low- and middle-income settings, updated survival data in acute lymphoblastic leukemia, and advances in hematopoietic cell transplantation using haploidentical and T-cell-depleted grafts. Special sessions addressed CNS tumors, lymphomas, survivorship, gene therapy, and qualitative research. Advocacy panels highlighted equity and access for displaced and conflict-affected populations. Regional initiatives included strengthening the POEM Palliative Care and achieving consensus on early cancer detection strategies aligned with the WHO GICC. Pre- and post-conference workshops on artificial intelligence, sarcoma management, nursing leadership, and retinoblastoma delivered hands-on training and reinforced regional capacity building. Workshop evaluations demonstrated strong learning outcomes and a high likelihood of practice change. CONCLUSION: The 2025 POEM Biennial Conference reaffirmed the network's role as a catalyst for advancing childhood cancer care across the Eastern Mediterranean. By integrating scientific advances with strategies for equity, access, and policy reform, POEM continues to accelerate progress toward the global target of achieving at least 60% survival for all children with cancer by 2030.
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