Selinexor 增强 NK 细胞对多发性骨髓瘤的活化
Selinexor potentiates NK cell activation against multiple myeloma.
这些数据揭示,selinexor 选择性破坏 MM 中的 2A:HLA-E 免疫检查点轴,并增强 NK 细胞活化以及对 MM 细胞的 ADCC。
肿瘤细胞治疗研究
FRONTIER PAPERS
近 5 年肿瘤细胞治疗领域的研究论文。默认按评分排序(权威性 + 新鲜度)。
Selinexor potentiates NK cell activation against multiple myeloma.
这些数据揭示,selinexor 选择性破坏 MM 中的 2A:HLA-E 免疫检查点轴,并增强 NK 细胞活化以及对 MM 细胞的 ADCC。
Second-line axicabtagene ciloleucel in large B-cell lymphoma ineligible for transplantation: ALYCANTE final analysis.
Neurotoxicity and cognitive outcomes in modern therapies for primary central nervous system lymphoma.
Association between CAR T-cell persistence and improved response to salvage radiotherapy in patients with DLBCL.
sRT 可能为 CAR-T 细胞治疗后复发的 DLBCL 提供持久的局部控制。复发时持续的 CAR-T 细胞活性可能有助于识别最可能从综合性 sRT 中获益的患者。鉴于队列规模小且异质性大,这些发现属于假设生成性,需要在更大规模系列中验证。
Independent validation of the International Metabolic Prognostic Index (CAR-IMPI) in patients with aggressive diffuse large B-cell lymphoma treated wi
High-dimensional spectral flow cytometry uncovers progressive T-cell exhaustion and myeloid cell reprogramming in a CLL mouse model.
Non-Malignant T Cells as Determinants of Immunotherapeutic Response in Chronic Lymphocytic Leukemia: Towards Personalized Strategies.
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