CELL INTELLIGENCE · 肿瘤细胞治疗研究

探索子宫内膜异位症相关菌群失调在子宫内膜癌发生中的可能作用

Exploring the Possible Role of Endometriosis-Associated Dysbiosis in Endometrial Carcinogenesis.

NK 细胞在子宫内膜癌肿瘤免疫逃逸与免疫治疗耐药交界处的作用

Natural killer cells at the interface of tumor immune escape and immunotherapy resistance in endometrial cancer.

间充质干细胞和 NK 细胞来源的细胞外囊泡对子宫内膜癌细胞顺铂反应性的差异效应

Differential Effects of Mesenchymal Stem Cell- and Natural Killer Cell-Derived Extracellular Vesicles on Cisplatin Responsiveness in Endometrial Cance

多组学分析将 DNA2 定位在泛癌中基因组完整性程序与肿瘤行为的交界处

Multi-omics analysis positions DNA2 at the interface of genome integrity programs and tumor behavior in pan-cancer.

ROBO1 CAR-NK92 细胞中 Cbl-b 敲除增强其抗肿瘤疗效

Ablation of Cbl-b in ROBO1 CAR-NK92 Cells Enhances Their Antitumor Efficacy.

PRIMMO 试验中接受 PD-1 阻断、放疗和免疫调节治疗的晚期宫颈癌与子宫内膜癌患者循环免疫细胞谱分析

Circulating immune cell profiling in advanced cervical and endometrial cancer patients treated with PD-1 blockade, radiotherapy, and immune modulation

纵向免疫变化，而非单纯的基线差异，可区分应答者与非应答者。

双向孟德尔随机化与单细胞 RNA 测序揭示 NK 细胞介导的子宫内膜异位症与子宫内膜癌之间的因果关联

Bidirectional Mendelian Randomization and Single‑Cell RNA Sequencing Reveal an NK Cell-Mediated Causal Link Between Endometriosis and Endometrial Canc

本研究支持子宫内膜异位症与子宫内膜癌之间存在由 NK 细胞特异性遗传机制介导的因果关联，BRI3 代表了一个潜在生物标志物和治疗靶点。需要进一步的功能研究和纵向队列研究来验证这些发现。

肿瘤微环境受肠促胰岛素和胰高血糖素的调节：代谢与免疫机制（综述）

Modulation of the tumor microenvironment by incretins and glucagon: Metabolic and immune mechanisms (Review).

肥胖与癌症：一项转化科学综述

Obesity and Cancer: A Translational Science Review.

超重和肥胖与更高的癌症发病率相关，在美国每年占新发癌症诊断的 10%。减重可能通过减轻肥胖的不良影响来降低癌症风险，但可能需要减重超过 10% 才能降低癌症风险。

祖先多样性自体患者来源类器官-免疫细胞共培养平台用于解决高级别子宫内膜癌免疫治疗结果差异

Ancestrally Diverse Autologous Patient-Derived Organoid-Immune Cell Coculture Platform for Addressing Immunotherapeutic Outcome Disparities in High-Gr