用于乳腺癌治疗的可注射水凝胶:从肿瘤微环境响应性与主动靶向药物递送到免疫治疗与诊疗一体化
Injectable Hydrogels for Breast Cancer Therapy: From Tumor Microenvironment-Responsive and Actively Targeted Drug Delivery to Immunotherapy and Theran
乳腺癌治疗仍面临诸多挑战,包括局部复发、全身毒性、肿瘤异质性、耐药和免疫抑制。
FRONTIER PAPERS
Injectable Hydrogels for Breast Cancer Therapy: From Tumor Microenvironment-Responsive and Actively Targeted Drug Delivery to Immunotherapy and Theran
乳腺癌治疗仍面临诸多挑战,包括局部复发、全身毒性、肿瘤异质性、耐药和免疫抑制。
CAR-T cell therapy in breast cancer management: expanding horizon and overcoming challenges beyond hematologic cancers.
乳腺癌(BC)仍然是发病率最高、治疗最具挑战性的癌症之一,目前的治疗方法往往受到治疗耐药和不良反应的限制。
AI-driven CRISPR strategies in breast cancer: Organoid modeling, adaptive editing, and precision delivery.
三阴性乳腺癌(TNBC)的定义是高度异质性、休眠的转移储库和快速的治疗耐药。
Development and validation of a prognostic 15-gene signature for stratifying HER2+/ER+ breast cancer.
这是首个对HER2+/ER+肿瘤进行分层的研究。总体而言,来自不同队列的初步结果显示,HER2+/ER+肿瘤中存在两个不同的亚组,可通过一个15基因特征进行区分。我们的发现可能有助于指导未来针对HER2+/ER+ BC的精准疗法的开发。
Progress and Prospect of Immunotherapy for Triple-Negative Breast Cancer.
TNBC仅占新发乳腺癌诊断的约15%-20%;
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