CELL INTELLIGENCE · 肿瘤细胞治疗研究

微流控 Cytotongue 系统实现肿瘤球体中 CAR-T 诱导机械软化的早期无标记检测

Microfluidic Cytotongue system enables early, label-free detection of CAR-T-induced mechanical softening in tumor spheroids.

深度生成模型增强 H&E 至 IHC 转化并稳健定量 TIL（肿瘤浸润淋巴细胞）：一项可行性研究

Enhancing Translation of H&E to IHC with Robust Tumor-Infiltrating Lymphocytes Quantification Using Deep Generative Models: A Feasibility Study.

两亲性脂质-单链 DNA 偶联物介导的细胞表面工程用于可编程细胞间连接和免疫突触形成

Amphiphilic Lipid-Single-Stranded DNA Conjugate-Mediated Cell Surface Engineering for Programmable Intercellular Tethering and Immune Synapse Formatio

乳腺癌化疗的转型：预测标志物、耐药机制和新的治疗方法

Breast cancer chemotherapy in transition: predictive markers, resistance mechanisms, and new treatment approaches.

一种肿瘤靶向七甲川花菁染料通过诱导致死性自噬抑制三阴性乳腺癌

A tumor-targeted heptamethine cyanine dye suppresses triple-negative breast cancer by induction of lethal autophagy.

本研究介绍了一种可能有效增强 TNBC 治疗效果的策略。

CD103+组织驻留记忆 T 细胞在肿瘤周边的空间相互作用与新辅助化疗后三阴性乳腺癌的临床结局相关

Spatial Interactions of CD103+ Tissue-Resident Memory T Cells in the Tumor Periphery Are Associated with Clinical Outcomes in Triple-Negative Breast C

肿瘤周边 CD103+与其他 T 细胞亚群之间的空间相互作用模式影响接受 NAC 治疗的 TNBC 患者的临床结局。分析 T 细胞之间此类空间关系，而非仅分析其是否存在，可能为接受 NAC 的患者提供额外的预后信息。

三阴性乳腺癌的免疫治疗：耐药机制与新兴方法：一项叙述性综述

Immunotherapy in triple-negative breast cancer: mechanisms of resistance and emerging approaches: a narrative review.

A2AR-phospho-STAT1 (Y701)-HLA-E 轴作为放疗抵抗性三阴性乳腺癌中潜在的免疫调节通路

A2AR-phospho-STAT1 (Y701)-HLA-E axis as a potential immune modulatory pathway in radiotherapy-resistant triple negative breast cancer.

放疗增加乳腺癌患者循环中细胞因子反应性增强的早期 NK 细胞

Radiation Therapy Increases Circulating Early-Stage Natural Killer Cells With Enhanced Cytokine Responsiveness in Breast Cancer.

RT 增加了循环中细胞因子响应的早期 NK 细胞，这与肿瘤内具有高 IFN-产生能力的终末分化细胞增加相关。这一发现揭示了乳腺癌中 RT 后 NK 细胞如何被调控。

聚焦超声触发的多柔比星脂质体重塑肿瘤微环境以增强三阴性乳腺癌模型中的检查点耗竭

Focused ultrasound-triggered doxorubicin liposomes reshape tumor microenvironment to boost checkpoint depletion in triple-negative breast cancer model