与黑色素瘤共培养后 GD2 特异性小鼠 CAR-T 细胞代谢的变化
Changes in the Metabolism of GD2-Specific Murine CAR-T Cells After Co-Culturing with Melanoma.
使用诱导性 CAR-T 细胞的免疫治疗,是在接近体内条件下抑制肿瘤的有效方法。
FRONTIER PAPERS
Changes in the Metabolism of GD2-Specific Murine CAR-T Cells After Co-Culturing with Melanoma.
使用诱导性 CAR-T 细胞的免疫治疗,是在接近体内条件下抑制肿瘤的有效方法。
CAR T-cell therapy in pediatric brain tumors: a narrative review with comparative analysis of clinical trial eligibility criteria.
符合纳入标准的研究共18项,包括临床前模型、早期临床试验和转化研究。
Targeting cancer stem cells with CAR-based immunotherapy: biology, evidence, and future directions.
癌症干细胞(CSCs)在肿瘤发生、进展和复发中起关键作用,凸显了靶向治疗以实现持久缓解的必要性。
Engineering CAR-T cells for solid tumors: Overcoming the microenvironment through integrated design and clinical translation.
CAR-T 细胞疗法在血液肿瘤中已取得显著的治疗效果,而其应用于实体恶性肿瘤仍受限于约9%的汇总客观缓解率。
The safety and efficacy of GD2-targeted CAR-T cells in patients with neuroblastoma: a systematic review and meta-analysis.
靶向 GD2 抗原的 CAR-T 细胞疗法在治疗 NB 方面前景广阔。
Comparative Preclinical Analysis of Anti-B7-H3 CAR-T Cells Targeting Neuroblastoma.
背景:神经母细胞瘤是一种儿童肿瘤,高危患者一旦复发通常致命。
GD2-Specific CAR T Cells Demonstrate Potent and Targeted Anti-Tumor Efficacy Against Melanoma In Vitro and In Vivo.
GD2.CAR T 细胞在体外和体内均对黑色素瘤表现出强效抗肿瘤活性,凸显了其治疗潜力,值得进一步开展临床研究。
Interplay Between the Epigenome, the Microenvironment, and the Immune System in Neuroblastoma.
神经母细胞瘤(NB)是儿童最常见的颅外肿瘤,也是儿童癌症死亡的第三大原因。
Updated Clinical Perspectives and Challenges of Chimeric Antigen Receptor-T Cell Therapy in Colorectal Cancer and Invasive Breast Cancer.
近年来,结直肠癌(CRC)和乳腺癌(BC)的发病率在全球范围内上升,并因缺乏选择性抗肿瘤疗法而导致更高的死亡率。
Targeting Tumor Glycans for Cancer Therapy: Successes, Limitations, and Perspectives.
异常糖基化是癌症的一个标志,并可能导致影响肿瘤行为的变化。
MEMBER ACCOUNT
登录成功会直接打开下一页。