CELL INTELLIGENCE · 肿瘤细胞治疗研究

共表达 IL-12 与 shVEGF 的溶瘤腺病毒增强免疫检查点阻断治疗肾细胞癌：体外、器官芯片与体内评价

Oncolytic adenovirus co-expressing IL-12 and shVEGF potentiates immune checkpoint blockade for treatment of renal cell carcinoma: in vitro, organ-on-a

打破胶质母细胞瘤的免疫隔离

Breaking immune isolation in glioblastoma.

溶瘤腺病毒联合 PD-L1 靶向放射免疫疗法对胰腺癌产生协同抗肿瘤效应

Oncolytic adenovirus in combination with PD-L1-targeted radioimmunotherapy exerts synergistic antitumor effect against pancreatic cancer.

我们的研究结果表明，HY-oAd 能以多方面的方式增强 177 Lu-aPD-L1 在肿瘤内的积聚，从而激发针对促结缔组织增生性和免疫原性差的胰腺肿瘤的协同抗肿瘤免疫反应。

肝细胞癌的治疗策略：当前进展与未来展望

Therapeutic Strategies for Hepatocellular Carcinoma: Current Advances and Future Perspectives.

癌症治疗中的基因编辑：克服耐药并提升精准医学

Gene editing in cancer therapy: overcoming drug resistance and enhancing precision medicine.

免疫刺激性溶瘤腺病毒介导的肿瘤微环境重塑增强免疫检查点抑制剂对免疫原性差的实体瘤的效力

Enhanced potency of immune checkpoint inhibitors against poorly immunological solid tumors by immune stimulatory oncolytic adenoviruses-mediated remod

紫杉醇偶联纳米杂合溶瘤腺病毒与树突状细胞疗法介导的协同抗肿瘤免疫应答

Synergistic antitumor immune response mediated by paclitaxel-conjugated nanohybrid oncolytic adenovirus with dendritic cell therapy.

靶向溶瘤病毒植入的 A56 病毒蛋白的嵌合抗原受体（CAR）-T 细胞开发

Development of chimeric antigen receptor (CAR)-T cells targeting A56 viral protein implanted by oncolytic virus.

编码 IFN-γ 和 CD47 的双臂溶瘤黏液瘤病毒促进同基因小鼠黑色素瘤的淋巴细胞浸润和肿瘤抑制

Dual-Armed Oncolytic Myxoma Virus Encoding IFN-γ and CD47 Promotes Lymphocyte Infiltration and Tumor Suppression of Syngeneic Murine Melanoma.

基于转座酶的分析揭示了 CAR-T 细胞的克隆行为与慢病毒载体整合位点的关联

Tagmentation-based analysis reveals the clonal behavior of CAR-T cells in association with lentivector integration sites.