CELL INTELLIGENCE · 肿瘤细胞治疗研究

更正：下一代 CAR-NK 细胞疗法：癌症免疫治疗中的工程策略、转化挑战与未来展望

Correction: Next-generation CAR-NK cell therapy: engineering strategies, translational challenges, and future perspectives in cancer immunotherapy.

肠道菌群对 IL-6/STAT3 通路的调控：将造血与结直肠癌进展联系起来

Gut microbiota regulation of the IL-6/STAT3 pathway: Linking hematopoiesis to colorectal cancer progression.

微生物群-IL-6/STAT3 界面建立了一个肠-骨髓-肿瘤轴，将菌群失调与造血改变及 CRC 进展联系起来。靶向该轴的综合策略具有前景，但需要进一步的安全性评估。

细菌 RNA 下调肿瘤细胞系 MHC-I 并促进 NK 反应、延缓肿瘤生长

Bacterial RNA downregulates MHC-I in tumor cell lines, promoting NK response and delaying tumor growth.

简要通讯：LSD1 抑制增强原发性 AML 细胞对 NK 细胞介导的杀伤的敏感性

Brief Communication: LSD1 Inhibition Enhances Susceptibility of Primary AML Cells for NK Cell-Mediated Killing.

NK 细胞与 CIK 细胞在血液系统恶性肿瘤中的比较机制、临床证据及转化前景

NK and CIK Cells in Hematologic Malignancies: Comparative Mechanisms, Clinical Evidence, and Translational Perspectives.

NK 细胞与 CIK 细胞可能提供互补而非直接竞争的益处。它们各自不同的功能特性为未来的联合或序贯策略提供了生物学依据。然而，需要前瞻性临床研究来明确它们在血液系统恶性肿瘤中的疗效、安全性、持久性及最佳临床应用。

过继性细胞疗法的新兴前沿：工程创新、当前挑战与制造视角

Emerging frontiers in adoptive cell therapies: engineering innovations, current challenges, and manufacturing perspectives.

异基因移植后急性髓系白血病复发中重编程失败的移植物抗白血病免疫的研究进展

Progress in reprogramming failed graft-versus-leukemia immunity in acute myeloid leukemia relapse after allogeneic transplantation.

利用全转录组学数据和下一代知识发现策略解读原发性卵巢癌的失调通路及候选治疗化合物

Deciphering the Dysregulated Pathways and Candidate Therapeutic Compounds for Primary Ovarian Cancer Using Whole Transcriptomics Data and Next Generat

抗 BCMA CAR-NK 细胞显示出对骨髓瘤细胞增强的溶细胞和分泌反应

Anti-BCMA CAR-NK Cells Reveal Enhanced Cytolytic and Secretory Responses Against Myeloma Cells.

胶质母细胞瘤中的先天免疫网络：细胞可塑性、免疫串扰及治疗意义

Innate immune networks in glioblastoma: Cellular plasticity, immune crosstalk, and therapeutic implications.