由 CAR-T 细胞来源外泌体与脂质体组成的序贯靶向杂合纳米囊泡用于增强肿瘤免疫化疗
Sequential Targeting Hybrid Nanovesicles Composed of Chimeric Antigen Receptor T-Cell-Derived Exosomes and Liposomes for Enhanced Cancer Immunochemoth
由于脂质体的肺靶向能力,静脉给药的 Lip-CExo@PTX 有超过 95% 蓄积于肺组织。
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按「中国试验优先 → 正在招募 → 更新更近」排序。信息来自 ClinicalTrials.gov 与 CDE 公开登记。能否入组、费用与可及性,以登记原文和主治医生判断为准。
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Sequential Targeting Hybrid Nanovesicles Composed of Chimeric Antigen Receptor T-Cell-Derived Exosomes and Liposomes for Enhanced Cancer Immunochemoth
由于脂质体的肺靶向能力,静脉给药的 Lip-CExo@PTX 有超过 95% 蓄积于肺组织。
Design and development of dual targeting CAR protein for the development of CAR T-cell therapy against KRAS mutated pancreatic ductal adenocarcinoma u
突变 KRAS 促进多种癌症的增殖、转移和侵袭性,包括胰腺导管腺癌(PDAC)、非小细胞肺癌(NSCLC)和结直肠腺癌(CRC)。
Tandem CAR-T cells targeting MUC1 and PSCA combined with anti-PD-1 antibody exhibit potent preclinical activity against non-small cell lung cancer.
嵌合抗原受体(CAR)-T 细胞在治疗实体瘤时面临诸多问题,包括肿瘤抗原异质性和免疫抑制。
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