CAR-T（CAR-T）细胞疗法在非肿瘤性疾病中的应用
Chimeric antigen receptor T (CAR-T) cell therapy in non-oncological diseases.
CELL INTELLIGENCE · 肿瘤细胞治疗研究
肿瘤细胞治疗研究
CAR-T 细胞治疗诱导一例合并慢性淋巴细胞白血病伴中枢神经系统受累及多发性硬化的患者完全缓解
英文原题：Chimeric antigen receptor T-cell therapy induces complete remission in a patient with concurrent CLL with CNS involvement and multiple sclerosis.
查看英文原题
Chimeric antigen receptor T-cell therapy induces complete remission in a patient with concurrent CLL with CNS involvement and multiple sclerosis.
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中文摘要
一例中枢神经系统受累的慢性淋巴细胞白血病（CLL）合并多发性硬化（MS）患者接受CD19靶向CAR-T 细胞治疗后，CLL达到完全缓解，MS疾病负担也显著改善。
展开英文摘要原文
In a patient with chronic lymphocytic leukemia (CLL) involving the central nervous system, and concurrent multiple sclerosis (MS), CD19-directed CAR T-cell therapy led to complete remission of CLL and marked improvement in MS disease burden.
论文信息
- 作者
- Murphy DJ、El Hussein S、Applebee A、Thomas A、Gerson JN
- 单位
- University of Vermont Cancer Center, University of Vermont Larner College of Medicine, Burlington, VT, USA.United States
- 文献类型
- 病例报告
- 期刊
- Leukemia & lymphoma2026 Aug
- 原文标识
- PubMed 42251699 · DOI 10.1080/10428194.2026.2682293