接受商业化 CAR-T 细胞治疗的中国淋巴瘤患者家庭照护者的负担、应对策略与未满足需求：一项定性研究

This study aimed to describe the caregiving experiences, coping strategies, and unmet health care needs of family caregivers supporting Chinese patients with large B-cell lymphoma receiving commercial chimeric antigen receptor T-cell therapy.

A qualitative descriptive design was adopted. Semistructured interviews were conducted with 19 primary family caregivers at a university-affiliated cancer centre in southern China. Data were analysed using Braun and Clarke's thematic analysis framework.

Three themes were identified: (1) overwhelming caregiving burden, including financial strain, emotional distress, and role conflict; (2) caregivers' patient-centred coping strategies, including familial financial sacrifice, emotional suppression to protect the patient, and reprioritizing work and personal life for care; and (3) unmet caregiver support needs, including navigating therapy costs without systemic support, gaps in caregiver education and care coordination, and caregivers' emotional support being overlooked in care systems.

Family caregivers of patients receiving this therapy in China experience significant challenges, which are often managed through culturally influenced coping strategies amid limited formal support. A caregiver-inclusive approach (including financial reforms, tailored caregiver education, increased care coordination, and psychosocial services) is essential to support the well-being of family caregivers and optimize treatment outcomes amid evolving oncology trends in China.