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细胞治疗的医疗旅游:临床视角

英文原题:Medical tourism for cellular therapy: a clinical perspective.

查看英文原题

Medical tourism for cellular therapy: a clinical perspective.

PubMed 2025/12/01(内容时间) Lancet Haematol Q1 · IF 20.4(JCR 2025)

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中文摘要

细胞治疗领域的医疗旅游呈指数级增长,尤其是在过去十年中,这得益于该领域的多项进展。本观点文章探讨了这一不断发展的领域,特别聚焦于造血干细胞移植(HSCT)和嵌合抗原受体(CAR)T细胞治疗。我们讨论了全球现状、监管挑战以及与医疗旅游相关的伦理考量。我们强调了医疗旅游在患者照护方面的益处和弊端,以及对当地医疗保健系统的影响。我们还探讨了受监管的、基于证据的细胞治疗与有风险的、未经证实的干细胞旅游之间的关键区别,后者利用弱势患者牟利。我们基于在一个区域性细胞治疗中心执业的经验提供了实用见解,并强调通过多学科团队、远程医疗整合和国际合作提供全面患者支持以改善患者结局的重要性。最后,我们就医疗旅游如何成为患者原籍国变革的催化剂以改善全球医疗保健公平性提供了观点和建议。

展开英文摘要原文

Medical tourism in the field of cellular therapy has been increasing exponentially, especially in the past decade, due to multiple advances in the field.

Our Viewpoint explores this growing field, with a specific focus on haematopoietic stem-cell transplantation (HSCT) and chimeric antigen receptor (CAR) T-cell therapy.

We discuss the global status, regulatory challenges, and ethical considerations associated with medical tourism.

We highlight benefits and drawbacks of medical tourism with regard to patient care and the impact on local health-care systems.

We also address the crucial distinction between regulated, evidence-based cellular therapies and risky, unproven stem-cell tourism, which preys on vulnerable patients.

We offer practical insights from our experience practicing in a regional cellular therapy hub and emphasise the importance of comprehensive patient support through a multidisciplinary team, telemedicine integration, and international collaboration to improve patient outcomes. Last, we provide perspective and suggestions on how medical tourism can be a catalyst for change within patients' countries of origin in order to improve global health-care equity.

论文信息

作者
Esther CHL、Fan EB、Hew YY、Poon LM
第一作者单位
Department of Hematology-Oncology, National University Cancer Institute, Singapore; National University of Singapore, Singapore.Singapore
通讯作者单位
Department of Hematology-Oncology, National University Cancer Institute, Singapore; National University of Singapore, Singapore. Electronic address: michelle_poon@nuhs.edu.sg.Singapore
文献类型
综述
期刊
The Lancet. Haematology2025 Dec
原文标识
PubMed 41338866 · DOI 10.1016/S2352-3026(25)00294-7