CAR-T（CAR-T）细胞疗法在非肿瘤性疾病中的应用
Chimeric antigen receptor T (CAR-T) cell therapy in non-oncological diseases.
CAR-T（CAR-T）细胞在血液系统恶性肿瘤中的应用推动了这种免疫治疗形式的显著进展。
CELL INTELLIGENCE · 肿瘤细胞治疗研究
肿瘤细胞治疗研究
慢性淋巴细胞白血病的免疫治疗
英文原题：Immunotherapy in Chronic Lymphocytic Leukemia.
查看英文原题
Immunotherapy in Chronic Lymphocytic Leukemia.
分数与星级只用于站内排序 —— 不代表疗效、安全性或个人适用性。
中文摘要
免疫疗法已重新定义多种淋巴瘤（包括慢性淋巴细胞白血病，CLL）及小淋巴细胞淋巴瘤（SLL）的治疗策略。本综述概述免疫疗法在 CLL/SLL 中的发展历程和疗效，尤其关注新型单克隆抗体、双特异性抗体及CAR-T 细胞疗法。
展开英文摘要原文
Immune-based therapies have redefined treatment strategies for a number of lymphomas including chronic lymphocytic leukemia (CLL) and small lymphocytic lymphoma (SLL). This review highlights the evolution and efficacy of immune-based therapies in CLL/SLL, especially the novel monoclonal antibodies, bispecific antibodies, and chimeric antigen receptor T-cell therapy.
论文信息
- 作者
- Sworder B、Siddiqi T
- 第一作者单位
- Division of Lymphoma, Department of Hematology & Hematopoietic Cell Transplantation, City of Hope National Medical Center, 1500 E. Duarte Road, Duarte, CA 91010, USA.United States
- 通讯作者单位
- Division of Lymphoma, Department of Hematology/HCT, City of Hope Orange County, 1000 Fivepoint, Irvine, CA 92618, USA. Electronic address: tsiddiqi@coh.org.United States
- 文献类型
- 综述 · 非美国政府资助研究
- 期刊
- Hematology/oncology clinics of North America2025 Oct
- 原文标识
- PubMed 40634160 · DOI 10.1016/j.hoc.2025.05.010