CELL INTELLIGENCE · 肿瘤细胞治疗研究
肿瘤细胞治疗研究
英文原题:Benign tumors broaden the field of application for immunotherapy.
Benign tumors broaden the field of application for immunotherapy.
分数与星级只用于站内排序 —— 不代表疗效、安全性或个人适用性。
免疫疗法在治疗恶性肿瘤方面已显示出巨大潜力。尚未被广泛考虑的是将免疫疗法用于治疗良性肿瘤的机会。通过聚焦于与特定良性肿瘤相关的特定遗传改变后所表达的可靶向抗原,免疫疗法可能为良性肿瘤治疗提供一种有效途径,从而避免更传统的手术需求。免疫疗法能够特异性识别并靶向肿瘤细胞,鉴于治疗可用的时间窗口较长,这对良性肿瘤尤其有益。因此,良性肿瘤因提供了更大的治疗机会窗口,且具有与有限突变负荷相关的相对稳定的表型,可以从针对每种病症独特相关抗原的免疫治疗策略中获得巨大益处。
Immunotherapy has shown significant potential for treating malignancies. Not yet widely considered is the opportunity to employ immunotherapy for the treatment of benign tumors.
By focusing on targetable antigens expressed following specific genetic changes associated with individual benign tumors, immunotherapy may provide an effective approach to benign tumor treatment, circumventing the need for more conventional surgery. Immunotherapies can specifically recognize and target tumor cells, which could be especially beneficial for benign tumors given the extended timeframe available for treatment.
Thus, benign tumors, offering a greater window of opportunity for treatment and a relatively stable phenotype associated with a limited mutation burden, can derive great benefit from immunotherapeutic approaches targeting antigens uniquely associated with each condition.
在 PubMed 查看 → 出版商原文(DOI) 全文 PDF(PMC)· 可下载 治疗专题与资料阅读指南 资料来源与翻译说明 报告译文或资料问题 →
MEMBER ACCOUNT
登录成功会直接打开下一页。