关于脂质体米托蒽醌治疗复发/难治性 T 细胞/NK 细胞淋巴瘤中干细胞动员的担忧

不适合移植的大 B 细胞淋巴瘤二线使用 axicabtagene ciloleucel：ALYCANTE 最终分析

Second-line axicabtagene ciloleucel in large B-cell lymphoma ineligible for transplantation: ALYCANTE final analysis.

与 CAR-T 细胞治疗后感染风险相关的宿主免疫生物标志物

Host immune biomarkers associated with infection risk after CAR T-cell therapy.

纵向免疫分析识别出与感染风险和 CAR-T 相关毒性相关的不同免疫学特征。这些发现提示免疫监测在改善风险分层和指导 CAR-T 治疗后支持治疗方面具有作用。

RNF43 p.G659fs 通过 PI3K/AKT/mTOR 信号通路和 HLA-E 上调导致 MSI-high 结直肠癌中 NK 细胞功能障碍

RNF43 p.G659fs leads to natural killer cell dysfunction in MSI-high colorectal cancer through PI3K/AKT/mTOR signaling and HLA-E up-regulation.

CD81 通过阻断 CD274/PD-L1 的选择性自噬降解驱动放射抵抗性胶质母细胞瘤的免疫逃逸

CD81 drives immune evasion in radioresistant glioblastoma by blocking selective autophagic degradation of CD274/PD-L1.

靶向白血病干细胞的脂质体纳米免疫疗法通过沉默 B 细胞淋巴瘤 2 逆转免疫逃逸并抑制融合癌蛋白驱动的急性髓系白血病

Leukemic Stem Cell-Targeted Liposomal Nanoimmunotherapy Reverses Immune Evasion and Inhibits Fusion Oncoprotein-Driven Acute Myeloid Leukemia by Silen

靶向巨噬细胞的癌症治疗策略

Macrophage-directed therapeutic strategies in cancer.