肿瘤细胞治疗研究
英文原题：Emerging strategies to overcome ovarian cancer: advances in immunotherapy.
Emerging strategies to overcome ovarian cancer: advances in immunotherapy.
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卵巢癌是第二常见的妇科恶性肿瘤，也是全球女性生殖系统癌症死亡的首要原因。这一现状很大程度上源于诊断较晚（常处于晚期）以及癌细胞产生化疗耐药。上述挑战凸显替代疗法的必要性，免疫治疗是一种有前景的选择。癌症免疫治疗旨在触发抗肿瘤免疫应答并建立免疫记忆，从而清除恶性细胞、预防复发并抑制转移。目前有一些研究正在探索癌症疫苗、免疫检查点阻断、CAR-T 细胞及其他策略等领域中潜在的免疫治疗进展。
Ovarian cancer is the second most common malignant neoplasm of gynecological origin and the leading cause of death from cancer in the female reproductive system worldwide. This scenario is largely due to late diagnoses, often in advanced stages, and the development of chemoresistance by cancer cells. These challenges highlight the need for alternative treatments, with immunotherapy being a promising option.
Cancer immunotherapy involves triggering an anti-tumor immune response and developing immunological memory to eliminate malignant cells, prevent recurrence, and inhibit metastasis. Some ongoing research investigate potentially immunological advancements in the field of cancer vaccines, immune checkpoint blockade, CAR-T cell, and other strategies.
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