CELL INTELLIGENCE · 肿瘤细胞治疗研究
肿瘤细胞治疗研究
PDT 与抗肿瘤免疫：故事的开始
英文原题：PDT and antitumor immunity: the beginnings of the story.
查看英文原题
PDT and antitumor immunity: the beginnings of the story.
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中文摘要
这篇小型综述简要描述了Canti团队关于光动力疗法在产生抗癌免疫中作用的首批实验。它首次强调了PDT在诱导抗肿瘤T淋巴细胞中的有效作用，并表明这种效应具有肿瘤特异性。还报道了这种过继免疫如何提高化疗疗效。这些研究有助于开辟一个重要的科学研究新领域，即PDT生成免疫的作用，并推动了当今重要的新临床前方法。
展开英文摘要原文
This mini-review reports a brief description of the first experiments conducted by Canti's group on the role of photodynamic therapy in generating immunity against cancer. It highlights for the first time the effective role of PDT in the induction of anti-tumor T lymphocytes and shows that this effect is tumor-specific.
It has also been reported how this adoptive immunity can improve the efficacy of chemotherapy. These studies have helped to open an important new field of scientific research on the role of PDT-generated immunity and to stimulate today's important new pre-clinical approaches.
论文信息
- 作者
- Canti G、Rapozzi V
- 第一作者单位
- Department of Medical Biotechnology and Translational Medicine, University of Milano, 20129, Milan, Italy. gianfranco.canti@unimi.it.Italy
- 通讯作者单位
- Department of Medicine, University of Udine, 33100, Udine, Italy. valentina.rapozzi@uniud.it.Italy
- 文献类型
- 综述
- 期刊
- Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology2024 Sep
- 原文标识
- PubMed 39235681 · DOI 10.1007/s43630-024-00627-1