← 返回

侵袭性 B 细胞淋巴瘤的 CAR-T 细胞治疗

英文原题:Chimeric antigen receptor T-cell therapy for aggressive B-cell lymphomas.

查看英文原题

Chimeric antigen receptor T-cell therapy for aggressive B-cell lymphomas.

PubMed 2024/07/01(内容时间) Front Oncol Q2 · IF 3.4(JCR 2025)

分数与星级只用于站内排序 —— 不代表疗效、安全性或个人适用性。

中文摘要

嵌合抗原受体(CAR)T 细胞疗法是治疗淋巴瘤的一种突破性方法。本综述概述了美国 FDA 批准用于侵袭性 B 细胞淋巴瘤的 4 种 CAR-T 细胞产品,包括用于弥漫性大 B 细胞淋巴瘤和套细胞淋巴瘤的产品,并介绍其疗效、毒性及未来发展方向。

展开英文摘要原文

Chimeric antigen receptor (CAR) T-cell therapy is a revolutionary approach in the treatment of lymphoma. This review article provides an overview of the four FDA-approved CAR T-cell products for aggressive B-cell lymphoma, including diffuse large B-cell lymphoma and mantle cell lymphoma, highlighting their efficacy and toxicity as well as discussing future directions.

论文信息

作者
Hu B、Korsos V、Palomba ML
第一作者单位
Department of Hematologic Oncology and Blood Disorders, Atrium Health Levine Cancer Institute/Wake Forest School of Medicine, Charlotte, NC, United States.United States
通讯作者单位
Cellular Therapy Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, United States.United States
文献类型
综述
期刊
Frontiers in oncology2024
原文标识
PubMed 39011476 · DOI 10.3389/fonc.2024.1394057