CAR-T（CAR-T）细胞疗法在非肿瘤性疾病中的应用
Chimeric antigen receptor T (CAR-T) cell therapy in non-oncological diseases.
CELL INTELLIGENCE · 肿瘤细胞治疗研究
肿瘤细胞治疗研究
淋巴瘤患者的长轴视野 PET 成像：挑战与机遇
英文原题：Long-Axial Field-of-View PET Imaging in Patients with Lymphoma: Challenges and Opportunities.
查看英文原题
Long-Axial Field-of-View PET Imaging in Patients with Lymphoma: Challenges and Opportunities.
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中文摘要
[18F]氟-2-脱氧-D-葡萄糖 PET/计算机断层扫描已应用于淋巴瘤患者的管理，能够提供淋巴瘤的实时代谢信息，有望实现更准确的分期、治疗反应评估、预后判断以及疾病复发的早期检测。淋巴增殖性疾病的临床管理近来已从初始化疗迅速演变至免疫治疗、靶向药物以及CAR-T 细胞疗法的应用。这些新系统和成像方案的实施，连同新型示踪剂的开发，在淋巴增殖性疾病领域既创造了机遇也带来了挑战，本综合文献综述将对此进行详细阐述。
展开英文摘要原文
[ 18 F]fluoro-2-deoxy-d-glucose PET/computed tomography has been implemented in the management of patients with lymphoma, offering real-time metabolic information on lymphoma with the promise of more accurate staging, treatment response assessment, prognostication, and early detection of disease recurrence.
The clinical management of lymphoproliferative disease has recently, rapidly evolved from initial chemotherapeutic to the use of immunotherapy, targeted agents, and to the use of chimeric antigen receptor T-cell therapies. The implementation of these new systems and imaging protocols together with new tracer development creates, in the field of lymphoproliferative disease, both opportunities and challenges that will be detailed in this comprehensive literature review.
论文信息
- 作者
- Mingels C、Nalbant H、Sari H、Godinez F、Sen F、Spencer B、Esteghamat NS、Tuscano JM
- 单位
- Department of Radiology, University of California Davis, Sacramento, CA, USA; Department of Nuclear Medicine, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland. Electronic address: cmingels@ucdavis.edu.United States
- 文献类型
- 综述
- 期刊
- PET clinics2024 Oct
- 原文标识
- PubMed 38969563 · DOI 10.1016/j.cpet.2024.05.005
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