间皮素作为癌症免疫治疗的生物标志物和治疗靶点
Mesothelin as Biomarker and Therapeutic Target for Immunotherapy in Cancer.
癌症仍是一个关键的全球健康问题，原因在于发现晚、耐药和高死亡率。
CELL INTELLIGENCE · 肿瘤细胞治疗研究
肿瘤细胞治疗研究
NK 细胞联合化疗治疗胃癌根治术后转移的疗效：病例报告
英文原题：Efficacy of nature killer cell combination chemotherapy for post-radical gastric cancer metastases: Case report.
查看英文原题
Efficacy of nature killer cell combination chemotherapy for post-radical gastric cancer metastases: Case report.
分数与星级只用于站内排序 —— 不代表疗效、安全性或个人适用性。
中文摘要
NK 细胞疗法近年来在肿瘤学领域显示出强大的疗效，并已应用于转移患者，旨在改善晚期胃癌的预后。一名59岁男性胃腺癌伴胰腺转移（T4N0M1）患者，曾接受胃癌根治术及肿瘤转移灶手术，接受奥沙利铂和替加氟联合细胞回输的分阶段治疗。治疗疗程后持续监测计算机断层扫描和血清肿瘤标志物。经过五个疗程的联合治疗后，患者处于疾病控制状态，无明显副作用。末次随访时，甲胎蛋白已恢复正常值，胰腺体部低密度影显示不佳。胰腺癌起病隐匿，死亡率高。该报告为胰腺转移癌的细胞治疗提供了临床证据，改善了生活质量。
展开英文摘要原文
Nature killer cell therapy has shown strong efficacy in the field of oncology in recent years and has been applied to patients with metastases with the aim of improving the prognosis of advanced gastric cancer. A 59-year-old male with gastric adenocarcinoma with pancreatic metastasis (T4N0M1) who underwent radical surgery for gastric cancer with tumor metastasis was treated with oxaliplatin and tegafur combined with cellular reinfusion in stages.
Computed tomograpy scan and serum tumor markers were monitored continuously after the treatment course. After five courses of combined treatment, the patient was in disease control with no significant side effects. At the last follow-up, the alpha fetoprotein had returned to its normal value with a poor display of low-density shadows in the body of the pancreas. Pancreatic cancer is insidious in origin and has a high mortality rate. The report provides clinical evidence for cell therapy of pancreatic metastatic cancer with improved quality of life.
论文信息
- 作者
- Yue Y、Zi M、Feng J、Wang W、Ren Z、Wu C、Yang Z
- 第一作者单位
- North China University of Science and Technology, Tangshan, China.China
- 通讯作者单位
- NHC Key Laboratory of Biotechnology of Antibiotics, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences, Beijing, China.China
- 文献类型
- 病例报告
- 期刊
- SAGE open medical case reports2024
- 原文标识
- PubMed 38803362 · DOI 10.1177/2050313X241254743
在 PubMed 查看 → 出版商原文（DOI） 全文 PDF（PMC）· 可下载 治疗专题与资料阅读指南 资料来源与翻译说明 报告译文或资料问题 →