CAR-T(CAR-T)细胞疗法在非肿瘤性疾病中的应用
Chimeric antigen receptor T (CAR-T) cell therapy in non-oncological diseases.
CAR-T(CAR-T)细胞在血液系统恶性肿瘤中的应用推动了这种免疫治疗形式的显著进展。
CELL INTELLIGENCE · 肿瘤细胞治疗研究
肿瘤细胞治疗研究
英文原题:InsT-ALLing CD7 chimeric antigen receptors before transplantation.
InsT-ALLing CD7 chimeric antigen receptors before transplantation.
分数与星级只用于站内排序 —— 不代表疗效、安全性或个人适用性。
作者在文中介绍了使用靶向 CD7 的CAR-T 细胞作为复发/难治性 T 细胞急性淋巴细胞白血病/淋巴母细胞淋巴瘤患者异基因造血细胞移植桥接的经验。评论:Cao 等。异基因造血干细胞移植用于自体 CD7 CAR-T 细胞治疗后达到完全缓解的难治性和复发性 T 细胞急性淋巴细胞白血病/淋巴母细胞淋巴瘤患者的安全性和有效性研究。Br J Haematol 2024;204:2351-2364。
In their paper, the authors present their experience with the use of chimeric antigen receptor T cells targeting CD7 as a bridge to allogeneic haematopoietic cell transplantation in patients with relapsed/refractory T-cell acute lymphoblastic leukaemia/lymphoblastic lymphoma. Commentary on: Cao et al.
A safety and efficacy study of allogeneic haematopoietic stem cell transplantation for refractory and relapsed T-cell acute lymphoblastic leukaemia/lymphoblastic lymphoma patients who achieved complete remission after autologous CD7 chimeric antigen receptor T-cell therapy. Br J Haematol 2024;204:2351-2364.
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