CELL INTELLIGENCE · 肿瘤细胞治疗研究
肿瘤细胞治疗研究
英文原题：Immunotherapy for Ovarian Cancer: Disappointing or Promising?
Immunotherapy for Ovarian Cancer: Disappointing or Promising?
分数与星级只用于站内排序 —— 不代表疗效、安全性或个人适用性。
卵巢癌是最致命的恶性肿瘤之一，尽管手术技术和化疗取得了进步，但仍缺乏有效的治疗方法。因此，迫切需要新的治疗策略来改善治疗结果。免疫疗法已在多种癌症的治疗中展现出显著成效，并已在临床实践中占有一席之地。本综述旨在概述卵巢肿瘤免疫治疗，包括其基本原理、关键策略以及支持其潜力的临床研究数据。特别地，本讨论强调了检查点抑制剂、疫苗和细胞转移等有前景的策略，无论是单独使用还是联合应用。然而，新型免疫疗法的进步需要进行大规模对照随机试验，这无疑将塑造卵巢癌治疗的未来。
Ovarian cancer, one of the deadliest malignancies, lacks effective treatment, despite advancements in surgical techniques and chemotherapy.
Thus, new therapeutic approaches are imperative to improving treatment outcomes. Immunotherapy, which has demonstrated considerable success in managing various cancers, has already found its place in clinical practice. This review aims to provide an overview of ovarian tumor immunotherapy, including its basics, key strategies, and clinical research data supporting its potential. In particular, this discussion highlights promising strategies such as checkpoint inhibitors, vaccines, and pericyte transfer, both individually and in combination.
However, the advancement of new immunotherapies necessitates large controlled randomized trials, which will undoubtedly shape the future of ovarian cancer treatment.
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