关注声明：抗 CD30 CAR-T 细胞治疗后复发经典霍奇金淋巴瘤中 CD30 表达常降低

Marques-Piubelli, M. L. , Kim, D. H. , Medeiros, L. J. , Lu, W. , Khan, K. , Gomez-Bolanos, L. I. , Rodriguez, S. , Parra, E. R. , Ok, C. Y. , Aradhya, A. , Solis, L. M. , Nieto, Y. L. , Steiner, R. , Ahmed, S. and Vega, F. (2023), CD30 expression is frequently decreased in relapsed classic Hodgkin lymphoma after anti-CD30 CAR T-cell therapy. Histopathology, 83: 143-148. https://doi. org/10. 1111/his. 14910 This Expression of Concern is for the above article, published online on 30 March 2023 in Wiley Online Library (wileyonlinelibrary.

com), and has been published by agreement between the journal Editor-in-Chief, Daniel Berney and John Wiley & Sons Ltd. The Expression of Concern has been agreed due to concerns raised by a third party regarding duplicated sections within some of the panels of Figure 1.

The authors admitted to these image alterations which were performed to enhance the visual appearance of the images (correcting folded areas or filling in blank spaces). The authors were able to provide the original, unmodified images and stated that they did not want to misrepresent the critical data or to compromise the scientific integrity of the manuscript.

However, the modification of the images to change the appearance is clearly against the ethical policy of Histopathology and Wiley's Best Practice Guidelines on Research Integrity and Publishing Ethics.

Therefore, the journal has decided to issue an Expression of Concern to inform and alert the readers.