不适合移植的大 B 细胞淋巴瘤二线使用 axicabtagene ciloleucel:ALYCANTE 最终分析
Second-line axicabtagene ciloleucel in large B-cell lymphoma ineligible for transplantation: ALYCANTE final analysis.
CELL INTELLIGENCE · 肿瘤细胞治疗研究
肿瘤细胞治疗研究
英文原题:Recent Advances in Nanobiotechnology for the Treatment of Non-Hodgkin's Lymphoma.
Recent Advances in Nanobiotechnology for the Treatment of Non-Hodgkin's Lymphoma.
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淋巴瘤是全球第八常见的癌症,主要分为霍奇金淋巴瘤(HL)和非霍奇金淋巴瘤(NHL),其中NHL约占80%–90%。NHL主要包括B细胞、T细胞和自然杀伤(NK)细胞淋巴瘤。纳米技术快速发展,并为医学领域作出重要贡献。本文综述近年来纳米生物技术的进展及其在NHL治疗中的应用,重点关注弥漫性大B细胞淋巴瘤(DLBCL)、原发性中枢神经系统淋巴瘤(PCNSL)和滤泡性淋巴瘤(FL)。讨论的技术包括临床影像、靶向药物递送、光动力治疗(PDT)和热动力治疗(TDT),旨在加深对纳米技术治疗非霍奇金淋巴瘤应用的认识。
Lymphoma is the eighth most common type of cancer worldwide. Currently, lymphoma is mainly classified into two main groups: Hodgkin's lymphoma (HL) and non-Hodgkin's lymphoma (NHL), with NHL accounting for 80% to 90% of the cases. NHL is primarily divided into B, T, and natural killer (NK) cell lymphoma. Nanotechnology is developing rapidly and has made significant contributions to the field of medicine.
This review summarizes the advancements of nanobiotechnology in recent years and its applications in the treatment of NHL, especially in diffuse large B cell lymphoma (DLBCL), primary central nervous system lymphoma (PCNSL), and follicular lymphoma (FL). The technologies discussed include clinical imaging, targeted drug delivery, photodynamic therapy (PDT), and thermodynamic therapy (TDT) for lymphoma. This review aims to provide a better understanding of the use of nanotechnology in the treatment of non-Hodgkin's lymphoma.
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