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晚期癌症治疗付费的综述:亚洲的严峻事实与现实

英文原题:A review on paying for advanced cancer therapeutics: hard truths and realities in Asia.

查看英文原题

A review on paying for advanced cancer therapeutics: hard truths and realities in Asia.

PubMed 2023/07/31(内容时间) Chin Clin Oncol Q3 · IF 2.7(JCR 2025)

分数与星级只用于站内排序 —— 不代表疗效、安全性或个人适用性。

中文摘要

由于新型癌症治疗药物价格高昂,且全球人口增长和老龄化带动药物使用增加,许多国家的癌症药物卫生系统支出正快速上升。癌症照护费用的增速持续超过其他疾病,给治疗可及性和癌症结局带来全球性挑战。亚洲各地药品定价差异显著,其中低收入和中等收入国家受到的影响尤为严重。肿瘤药物亟需实行基于价值的定价,以激励高价值药物研发并减少浪费。为实现癌症照护全民健康覆盖,亚洲国家可采取的措施包括开展基于价值的评估、建设支持合理优先排序的融资基础设施、建立本土创新与生产能力,以及降低单位照护成本。亚洲还需持续推进聚焦药品定价的成本管理措施,同时鼓励探索其他干预方式,例如集中专业力量,通过 CAR-T 细胞治疗等学习曲线较长的疗法实现效率提升。文章呼吁亚洲国家加强国际合作,并持续开展各国内部公众沟通,以确保人们公平获得有效的癌症药物。

展开英文摘要原文

Health system expenditure on cancer drugs is rising rapidly in many countries given the high-priced novel treatments as well as the increasing usage due to a growing and ageing global population. The cost of cancer care continues to outstrip other diseases and it presents a global challenge to treatment access and cancer outcomes. Substantial variability exists in drug pricing across Asia, with low- or middle-income countries being heavily impacted. There is an urgent need to practice value-based pricing for oncology drugs. This will incentivize development of higher-value medicine and eliminate waste.

Value-based assessments, financing infrastructure to assist appropriate prioritization, establishing domestic innovation and productive capabilities and reducing the unit economics of care are some of the measures that Asian countries should take towards ensuring universal health coverage for cancer care.

Asia will need to keep driving cost management measures that are focused on drug pricing and simultaneously, should be encouraged to explore other interventions including centralising expertise for high "learning curve" efficiencies like chimeric antigen receptor (CAR)-T cell therapy. There is a call for more international collaboration within Asia and a continuous need to engage the public within each country, in order to ensure equitable access to effective cancer medications.

论文信息

作者
Wong EYT、Lim JFY、Toh HC
单位
Division of Medical Oncology, National Cancer Centre Singapore, Singapore, Singapore.Singapore
文献类型
综述
期刊
Chinese clinical oncology2023 Aug
原文标识
PubMed 37574569 · DOI 10.21037/cco-23-37