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肿瘤免疫治疗的神经系统并发症

英文原题:Neurologic Complications of Cancer Immunotherapy.

查看英文原题

Neurologic Complications of Cancer Immunotherapy.

PubMed 2023/06/19(内容时间) Curr Oncol Q2 · IF 3.6(JCR 2025)

分数与星级只用于站内排序 —— 不代表疗效、安全性或个人适用性。

中文摘要

免疫治疗在过去十年中彻底改变了癌症治疗。随着其越来越多地进入常规临床实践,免疫相关并发症也变得更加常见。准确的诊断和治疗至关重要,目标是降低患者发病率。本综述旨在讨论与使用免疫检查点抑制剂、过继性T细胞疗法和T细胞重定向疗法相关的神经系统并发症的各种临床表现、诊断、治疗和预后。我们还概述了与这些药物临床使用相关的建议临床方法。

展开英文摘要原文

Immunotherapy has revolutionized cancer treatment over the past decade. As it is increasingly introduced into routine clinical practice, immune-related complications have become more frequent. Accurate diagnosis and treatment are essential, with the goal of reduced patient morbidity. This review aims to discuss the various clinical manifestations, diagnosis, treatments, and prognosis of neurologic complications associated with the use of immune checkpoint inhibitors, adoptive T-cell therapies, and T-cell redirecting therapies.

We also outline a suggested clinical approach related to the clinical use of these agents.

论文信息

作者
Alsalem AN、Scarffe LA、Briemberg HR、Aaroe AE、Harrison RA
单位
Division of Neurology, University of British Columbia, Vancouver, BC V6T 2B5, Canada.Canada
文献类型
综述
期刊
Current oncology (Toronto, Ont.)2023 Jun 19
原文标识
PubMed 37366923 · DOI 10.3390/curroncol30060440