CELL INTELLIGENCE · 肿瘤细胞治疗研究
肿瘤细胞治疗研究
实体上皮癌患者的过继性细胞转移免疫治疗
英文原题：Adoptive cell transfer immunotherapy for patients with solid epithelial cancers.
查看英文原题
Adoptive cell transfer immunotherapy for patients with solid epithelial cancers.
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中文摘要
将过继性细胞转移（ACT）免疫疗法应用于常见上皮癌患者的努力，受到了以下发现的推动：大多数此类患者体内含有针对其癌症突变表达产物具有反应性的淋巴细胞。早期针对这些抗原进行特异性靶向的努力已显示出良好前景。
展开英文摘要原文
Efforts to apply adoptive cell transfer (ACT) immunotherapy to patients with common epithelial cancers have been stimulated by the demonstration that the majority of these patients contain lymphocytes reactive against the expressed products of their cancer mutations. Early efforts to specifically target these antigens have been promising.
论文信息
- 作者
- Rosenberg SA、Parkhurst MR、Robbins PF
- 单位
- Surgery Branch, Center for Cancer Research, National Cancer Institute, Bethesda, MD, USA. Electronic address: sar@mail.nih.gov.United States
- 期刊
- Cancer cell2023 Apr 10
- 原文标识
- PubMed 37037613 · DOI 10.1016/j.ccell.2023.03.003
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