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癌症免疫治疗递送方式的最新进展

英文原题:Recent Advances in Cancer Immunotherapy Delivery Modalities.

查看英文原题

Recent Advances in Cancer Immunotherapy Delivery Modalities.

PubMed 2023/02/02(内容时间) Pharmaceutics Q1 · IF 6.9(JCR 2025)

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中文摘要

免疫疗法对于对抗癌症并实现成功缓解至关重要。近期涌现出许多新策略,但要通过诱导免疫级联反应有效攻击癌细胞并瓦解癌症微环境,仍有一些障碍需要克服。为成功发挥抗肿瘤活性,免疫细胞必须递送至癌细胞并能够接触免疫系统。此类尖端技术需要精心设计递送方法,确保递送过程中无损失或能够更有效地归巢至肿瘤环境,同时实现较高疗效并减少不良事件。本文讨论癌症免疫疗法递送技术的最新进展及其未来前景。

展开英文摘要原文

Immunotherapy is crucial in fighting cancer and achieving successful remission. Many novel strategies have recently developed, but there are still some obstacles to overcome before we can effectively attack the cancer cells and decimate the cancer environment by inducing a cascade of immune responses. To successfully demonstrate antitumor activity, immune cells must be delivered to cancer cells and exposed to the immune system.

Such cutting-edge technology necessitates meticulously designed delivery methods with no loss or superior homing onto cancer environments, as well as high therapeutic efficacy and fewer adverse events. In this paper, we discuss recent advances in cancer immunotherapy delivery techniques, as well as their future prospects.

论文信息

作者
Muthukutty P、Woo HY、Ragothaman M、Yoo SY
单位
BIO-IT Foundry Technology Institute, Pusan National University, Busan 46241, Republic of Korea.South Korea
文献类型
综述
期刊
Pharmaceutics2023 Feb 2
原文标识
PubMed 36839825 · DOI 10.3390/pharmaceutics15020504