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结外自然杀伤/T 细胞淋巴瘤侵犯患者心脏:一例罕见病例报告及文献复习

英文原题:Extranodal natural killer/T-cell lymphoma invading a patient's heart: A rare case report and literature review.

查看英文原题

Extranodal natural killer/T-cell lymphoma invading a patient's heart: A rare case report and literature review.

PubMed 2022/12/07(内容时间) Front Oncol Q2 · IF 3.4(JCR 2025)

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中文摘要

结外NK/T细胞淋巴瘤(ENKTL)是一种罕见但侵袭性强的非霍奇金淋巴瘤亚型,来源于NK细胞或T细胞。ENKTL侵犯心脏的病例极为罕见。英文文献中仅报道了12例ENKTL侵犯心脏的病例。由于该淋巴瘤的罕见性,尚未确定有效的治疗策略。本文报道一例51岁中国男性结外NK/T细胞淋巴瘤侵犯心脏的病例并进行文献复习。该患者接受了PD1单克隆抗体(信迪利单抗)联合一线P-Gemox方案的化疗。患者确诊后生存2个月。

展开英文摘要原文

Extranodal NK/T-cell lymphoma (ENKTL) is a rare but aggressive subtype of non-Hodgkin lymphoma, which is derived from NK cells or T cells. There are very few cases of ENKTL invading the heart. Only 12 cases of ENKTL invading the heart have been reported in the English literature. Due to the rarity of this lymphoma, an effective therapeutic strategy has not been defined.

Here, we present a case of a 51-year-old Chinese male with extranodal NK/T-cell lymphoma invading the heart and review the literature. The patient received a chemotherapy regimen of PD1 monoclonal antibody (Sintilimab) in combination with first-line P-Gemox. The patient survived for 2 months after diagnosis.

论文信息

作者
Xiang Y、Lin X、Cai X、Qu S、Lin KY
单位
Department of Cardiology, Fujian Provincial Hospital, Shengli Clinical Medical College of Fujian Medical University, Fuzhou, China.China
文献类型
病例报告
期刊
Frontiers in oncology2022
原文标识
PubMed 36568165 · DOI 10.3389/fonc.2022.1011894