不适合移植的大 B 细胞淋巴瘤二线使用 axicabtagene ciloleucel:ALYCANTE 最终分析
Second-line axicabtagene ciloleucel in large B-cell lymphoma ineligible for transplantation: ALYCANTE final analysis.
CELL INTELLIGENCE · 肿瘤细胞治疗研究
肿瘤细胞治疗研究
英文原题:Ptosis, facial numbness and parotid gland mass as the first symptoms of an extranodal NK/T cell lymphoma, nasal type.
Ptosis, facial numbness and parotid gland mass as the first symptoms of an extranodal NK/T cell lymphoma, nasal type.
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我们报告一例患者,因腮腺肿块、上睑下垂和面部麻木就诊于耳鼻喉科。CT 成像证实腮腺有一肿块;然而,同时也发现左侧上颌窦有一肿块。MRI、正电子发射断层扫描联合 CT 及鼻活检证实了结外 NK/T 细胞淋巴瘤,鼻型的诊断。由于这在西方社会是一种罕见的临床实体,患者通常在晚期才被诊断;症状类似于慢性鼻窦炎,且组织病理学分析具有挑战性。在这一非典型病例中,患者表现为上睑下垂、腮腺肿块和面部麻木的症状,而非鼻部症状。在本病例中,我们想强调诊断鼻窦 NK/T 细胞淋巴瘤往往具有挑战性。
We present a case of a patient visiting the ear, nose and throat department with a parotid gland mass, ptosis and facial numbness. CT imaging confirmed a mass in the parotid gland; however, it also revealed a mass in the left maxillary sinus. MRI, positron emission tomography combined with CT and nasal biopsy confirmed the diagnosis of a extranodal natural killer/T cell lymphoma, nasal type.
Because this is a rare clinical entity in Western society, patients are typically diagnosed in an advanced stage; symptoms resemble chronic rhinosinusitis and histopathological analysis is challenging. In this atypical case, the patient presented with symptoms of ptosis, parotid gland mass and facial numbness instead of nasal symptoms. In this case, we want to emphasise that diagnosing a sinonasal NK/T-cell lymphoma is often challenging.
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