CELL INTELLIGENCE · 肿瘤细胞治疗研究
肿瘤细胞治疗研究
英文原题：Immunotherapy in Ovarian Cancer.
Immunotherapy in Ovarian Cancer.
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尽管手术和化疗取得了进展，卵巢癌仍然是最致命的恶性肿瘤之一。因此，需要采用新的治疗方法来改善该疾病的预后。免疫疗法已被证明对许多肿瘤有效，并已纳入临床实践。在这篇综述中，我们描述了卵巢癌免疫治疗的关键策略，并总结了评估免疫学前景的临床研究数据，这些前景可能在未来改善卵巢癌的治疗方法。当前最显著的策略包括检查点阻断剂、疫苗的使用、过继性细胞转移，以及这些方法的各种组合。虽然其中一些选择很有前景，但仍需要大型对照随机研究才能将新的免疫治疗选择纳入临床实践。
Despite advances in surgery and chemotherapy, ovarian cancer remains one of the most lethal malignancies. Hence, the implementation of novel treatment approaches is required to improve the outcomes of the disease. Immunotherapy has been proven to be effective in many tumors and has already been incorporated into clinical practice.
In this review, we describe key strategies in immunotherapy of ovarian cancer and summarize data from clinical studies assessing immunological prospects which could improve ovarian cancer treatment approaches in the future. The most notable current strategies include checkpoint blockade agents, the use of vaccines, adoptive cell transfer, as well as various combinations of these methods. While several of these options are promising, large controlled randomized studies are still needed to implement new immunotherapeutic options into clinical practice.
在 PubMed 查看 → 出版商原文（DOI） 全文 PDF（PMC）· 可下载 治疗专题与资料阅读指南 资料来源与翻译说明 报告译文或资料问题 →
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