工程化益生菌用于肿瘤靶向联合化学免疫治疗
Engineered probiotics for tumor-targeted combination chemoimmunotherapy.
CELL INTELLIGENCE · 肿瘤细胞治疗研究
肿瘤细胞治疗研究
英文原题:Current State of Cell Therapies for Gastrointestinal Cancers.
Current State of Cell Therapies for Gastrointestinal Cancers.
分数与星级只用于站内排序 —— 不代表疗效、安全性或个人适用性。
过继性细胞疗法包括多种基于细胞的疗法,旨在利用免疫系统的力量产生强大的抗癌效果。检查点抑制在实体瘤中的早期成功增加了免疫疗法的研究与开发。由于抗原特异性和进入肿瘤微环境的挑战,基于细胞的疗法在胃肠道恶性肿瘤中的应用仍处于起步阶段。在这篇综述中,我们讨论了过继性细胞疗法在临床前和临床研究中的挑战和早期成功方面的现状。
Adoptive cell therapies include multiple cell-based therapies to harness the immune system's power to mount a robust anticancer effect. Early successes in solid tumors with checkpoint inhibition have increased the research and development of immunotherapy.
The utilization of cell-based therapy for gastrointestinal malignancies is still in its infancy because of challenges of antigen specificity and access to the tumor microenvironment. In this review, we discuss the current state of adoptive cell therapies in terms of challenges and early successes in preclinical and clinical studies.
MEMBER ACCOUNT
登录成功会直接打开下一页。